The Diagnosis and Treatment of Hair and Scalp Diseases

    Hans Wolff, Tobias W. Fischer, Ulrike Blume-Peytavi
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    TLDR Hair loss requires customized treatments based on its various causes and types.
    The document from 2016 reviews the causes, diagnosis, and treatment of hair and scalp diseases, particularly focusing on hair loss disorders. It identifies hair loss as either physiological or pathological, with a range of causes including hormonal imbalances, nutritional deficiencies, and infections. Androgenetic alopecia, the most common type, is characterized by patterned hair loss in men and diffuse thinning in women. Alopecia areata, an autoimmune condition, leads to patchy hair loss and has a variable prognosis influenced by factors like age of onset and extent of hair loss, with topical immune therapy being the most effective treatment. Scarring alopecias, such as folliculitis decalvans and lichen planopilaris, result in permanent hair loss and are treated with methods ranging from antimicrobial shampoos to surgical interventions. The document also notes the lack of evidence for certain treatments for female androgenetic alopecia and the potential of Janus kinase inhibitors for alopecia areata. It concludes that hair loss should be approached as a symptom requiring tailored treatments and is based on research and expert opinions up to 2016, with authors disclosing conflicts of interest related to honoraria and consultancy.
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      Diffuse hair loss and scalp biopsies

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      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community How essential is scalp biopsy when dealing with hair loss?

      in Treatment  6 upvotes 1 month ago
      The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

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