DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!
    Research/Science 2/5/2025

    At a glance
    In this educational post, the primary subjects mentioned are
    πŸ’Š Dutasteride (oral) 0.5mg - 2.5mg once per day
    β€’ Minoxidil (topical or oral) 5% topical or 0.25mg - 5mg per day
    πŸ’Š Pioglitazone (oral) 15mg - 30mg once per day
    πŸ’§ Clobetasol Propionate (topical) 0.05% once per day
    πŸ’§ Calcipotriol (topical) 0.005% once per day
    β€’ Ketoconazole (shampoo) 2% 4 times a week
    πŸ’Š Doxycycline (oral) 200 mg once or twice a day
    the tone is 😐 neutral.

    Other terms

    DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.
    View this post in the Community β†’

    Similar Community Posts Join

    5 / 277 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community DHEA, the culprit behind DUPA ? Read this!

      in Research/Science  18 upvotes 2 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community Scalp Biopsy Results - Almost 2 Years Dutasteride, Still Worsening

      in Update  24 upvotes 7 months ago
      Dutasteride and finasteride are not effectively stopping hair loss for some users, despite long-term use. Some are considering or using RU58841, pyrilutamide, and other treatments like microneedling, while also managing seborrheic dermatitis with diet and topical solutions.

      community 7 years minoxidil user. Is this the Time for HT ?

      in Progress Pictures  46 upvotes 2 years ago
      A 25-year-old has used minoxidil for 7 years, finasteride for 2 years, oral minoxidil and dutasteride for 3 months, and also tried microneedling and nizoral. They are considering a hair transplant but are concerned about being a good candidate due to potential retrograde alopecia.

    Related Research

    6 / 24 results