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GlossaryPioglitazone

medication for type 2 diabetes that increases insulin sensitivity

Pioglitazone, also known by the brand name Actos, is a medication used to manage type 2 diabetes. It works by increasing the body's sensitivity to insulin, helping to control blood sugar levels. While primarily used for diabetes, it has also been studied for potential benefits in other conditions, including certain types of hair loss like alopecia, due to its anti-inflammatory and insulin-sensitizing properties.

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Lichen Planopilaris Treated by the Peroxisome Proliferator-Activated Receptor-γ Agonist Pioglitazone: Lack of Lasting Improvement or Cure in the Majority of Patients

research Lichen Planopilaris Treated by the Peroxisome Proliferator-Activated Receptor-γ Agonist Pioglitazone: Lack of Lasting Improvement or Cure in the Majority of Patients

33 citations, October 2013 in “Journal of The American Academy of Dermatology”

Pioglitazone usually doesn't effectively treat or cure lichen planopilaris.

research Comparison of Clinical and Metabolic Effects of Metformin and Pioglitazone in Polycystic Ovary Syndrome

26 citations, January 2016 in “Indian journal of endocrinology and metabolism”

Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.

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community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 4 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.