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GlossaryFolliculitis Decalvans

chronic scalp condition causing inflamed follicles and permanent hair loss

Folliculitis Decalvans is a rare, chronic inflammatory condition that affects hair follicles, leading to scarring and permanent hair loss. It is characterized by painful, red, and inflamed pustules or sores on the scalp, often resulting in patches of baldness. The exact cause is unknown, but it is believed to involve bacterial infection and an abnormal immune response.

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research Folliculitis Decalvans: A Rare Inflammatory Scalp Disorder

112 citations, July 2008 in “Dermatologic Therapy”

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

research Folliculitis Decalvans: A Multicenter Review of 82 Patients

68 citations, February 2015 in “Journal of the European Academy of Dermatology and Venereology”

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

research Retrospective Review of Folliculitis Decalvans in 23 Patients with Course and Treatment Analysis of Long-Standing Cases

43 citations, January 2015 in “Journal of Cutaneous Medicine and Surgery”

Most patients improved with oral antibiotics, but some needed long-term treatment or had minimal response.

Folliculitis Decalvans: Effectiveness of Therapies and Prognostic Factors in a Multicenter Series of 60 Patients with Long-Term Follow-Up

research Folliculitis Decalvans: Effectiveness of Therapies and Prognostic Factors in a Multicenter Series of 60 Patients with Long-Term Follow-Up

41 citations, June 2018 in “Journal of The American Academy of Dermatology”

Some treatments for folliculitis decalvans work well, with tetracyclines and a mix of rifampicin and clindamycin being most effective.

research Updates in Therapeutics for Folliculitis Decalvans: A Systematic Review with Evidence-Based Analysis

40 citations, August 2018 in “Journal of the American Academy of Dermatology”

Clindamycin and rifampicin are the most effective treatments for folliculitis decalvans, but more research is needed.

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community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Seb derm regrowth progress? I think? Or am I just seeing what I want to see?

in Is this regrowth? 48 upvotes 7 months ago

A person with hair loss due to seborrheic dermatitis saw improvement after treating the condition and using 5mg oral minoxidil, topical minoxidil, collagen, biotin, and vitamins. They are asking if the progress is real, and others have noted the oral minoxidil as a significant treatment.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 61 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community How I paused my hair loss by curing seborrheic dermatitis

in Treatment 107 upvotes 1 year ago

User Wonderful_Tonight910 suffered from hair loss and seborrheic dermatitis for years. After using irritant-free shampoo, their scalp improved, hair loss stopped, and new hair growth appeared.

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