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    GlossaryJanus Kinase Inhibitors (JAK inhibitors)

    medications that block enzymes involved in immune response signaling

    Janus Kinase Inhibitors, often referred to as JAK inhibitors, are a class of medications that block the activity of Janus kinases, which are enzymes involved in the signaling pathways that regulate immune responses and inflammation. By inhibiting these enzymes, JAK inhibitors can help manage conditions like rheumatoid arthritis, psoriasis, and certain types of alopecia, where the immune system mistakenly attacks the body's own tissues.

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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      community DUPA - 20 YO - Non responder to everything

      in Finasteride/Dutasteride  13 upvotes 2 months ago
      A 20-year-old user experienced worsening hair loss despite using various treatments including topical and oral minoxidil, finasteride, and dutasteride. Other users suggested additional treatments like JAK inhibitors, RU58841, and lifestyle changes, but the user remains skeptical and frustrated.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Seriously, why is this man such an angel 😭

      in Satire  376 upvotes 1 month ago
      Dr. Gary Linkov, a YouTuber and doctor, is praised for his free hair loss advice despite his own struggles with hair loss. Some users discuss the high cost of his consultations and treatments like oral minoxidil and Jak inhibitors.