Search
for

    Glossary Topical JAK Inhibitors

    medications applied to skin to block Janus kinase enzymes

    Topical JAK Inhibitors, also known as Topical Janus Kinase Inhibitors or Topical JAKis, are medications applied directly to the skin to block the activity of Janus kinase enzymes. These enzymes play a role in the immune response and inflammation. By inhibiting them, these treatments can help manage conditions like alopecia areata, an autoimmune disorder that causes hair loss, by reducing inflammation and potentially promoting hair regrowth.

    Related Terms

    Research 10 of 1000+

    1. Topical JAK Inhibitors for the Treatment of Alopecia Areata and Vitiligo Current dermatology reports · 2017
    2. Review of the Literature: Topical JAK Inhibitors Showing Promise for Hair Loss! Hair transplant forum international · 2016
    3. 43647 Treatment of Refractory Folliculitis Decalvans with the Topical JAK Inhibitor Tofacitinib Journal of the American Academy of Dermatology · 2023
    4. Emerging Topical and Systemic JAK Inhibitors in Dermatology Frontiers in Immunology · 2019 · 277 citations
    5. Randomized Controlled Trial of the Topical Jak Inhibitor Delgocitinib Cream in Patients with Frontal Fibrosing Alopecia Journal of Investigative Dermatology · 2025 · 1 citations
    6. Clinical and Dermoscopic Evaluation of the Safety and Efficacy of Oral baricitinib (JAK Inhibitor) in Treatment of Localized Vitiligo Either Alone or with Topical Tacrolimus The Egyptian Journal of Hospital Medicine · 2025
    7. 126 Itch of Dermatomyositis treated with topical JAK inhibitor Journal of Investigative Dermatology · 2025
    8. Topical Janus kinase inhibitors: A review of applications in dermatology Journal of the American Academy of Dermatology · 2018 · 63 citations
    9. Treatment of alopecia universalis with topical Janus kinase inhibitors – a double blind, placebo, and active controlled pilot study International Journal of Dermatology · 2018 · 49 citations
    10. The efficacy and safety of JAK inhibitors for alopecia areata: A systematic review and meta-analysis of prospective studies Frontiers in pharmacology · 2022 · 37 citations
    All research results →

    Community 5 of 1000+

    1. 35M with alopecia areata - Treatments failing, next steps? Community · 20 Jul 2026
    2. DUPA - 20 YO - Non responder to everything Reddit · 14 Sept 2024
    3. The Worst Hair Loss Condition You (MAY) have: LPP Reddit · 31 Aug 2024
    4. Should I get transplant #4 or just shave my head? Reddit · 4 Aug 2024
    5. If RU58841 is such an effective anti androgen Reddit · 6 Jan 2024
    All community results →

    Learn 1 of 26

    1. Neem Oil Oil from the neem tree, used in traditional remedies
    All learn results →