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    GlossaryTopical Calcineurin Inhibitors

    medications applied to skin to reduce immune responses

    Topical Calcineurin Inhibitors (TCIs) are medications applied to the skin to reduce inflammation and immune responses. They work by blocking the activity of calcineurin, a protein that activates T-cells in the immune system, making them useful in treating conditions like eczema and vitiligo. Unlike corticosteroids, TCIs do not cause skin thinning, making them a safer long-term option for sensitive areas.

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      a novel topical treatment that inhibits DHT on androgen receptors

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      a potent but unapproved and potentially problematic topical anti-androgen

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      hormone commonly taken for sleep aid has some topical benefits for hair

    Research

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      research Treatment Of Frontal Fibrosing Alopecia

      January 2023 in “Dermatologic Therapy”
      Intralesional corticosteroids and 5-alpha-reductase inhibitors are the best treatments for frontal fibrosing alopecia.
      Innovative Therapeutics in Pediatric Dermatology

      research Innovative Therapeutics in Pediatric Dermatology

      8 citations , May 2010 in “Dermatologic clinics”
      New treatments for skin conditions in children include a preferred drug for birthmark reduction, proactive creams for eczema and vitiligo, a safe psoriasis medication, and special tissues and socks for eczema and fungal infections.

      research Pathophysiology of Vitiligo

      72 citations , November 1997 in “Clinics in dermatology”
      Vitiligo is a skin condition causing white patches, likely due to an autoimmune issue.

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