34 citations
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April 2001 in “PubMed” This study found that eflornithine HCl 13.9% cream reduces unwanted facial hair growth in women, with effects seen in up to 60% of participants over 4-8 weeks, with mostly minor skin irritation reported.
3 citations
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January 2000 in “Current Medical Research and Opinion” This research reported that eflornithine HCl 13.9% cream generally has a favorable dermal safety profile for managing unwanted facial hair in women, though it can cause mild irritation under certain conditions.
195 citations
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May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.
133 citations
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July 2006 in “International Journal of Dermatology” This study found that topical eflornithine HCl 13.9% cream effectively reduced facial hair in women, with a favorable safety profile.
132 citations
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September 2009 in “Experimental Dermatology” This study introduced a new classification system for distinguishing between anagen VI and early catagen stages in human hair follicle organ culture, using it to confirm eflornithine's ability to induce premature catagen.