Spironolactone
aka - Aldactone
Where to find Spironolactone
Tracking 2 topical products by companies like Minoxidil Express and MinoxidilMax. View all 2 products »Spironolactone is a versatile medication, traditionally used as a diuretic for treating conditions like hypertension and heart failure, but it also plays a significant role in dermatology and hair loss treatment. Known as a mineralocorticoid receptor antagonist and potassium-sparing diuretic with powerful anti-androgenic properties, it is also used for primary hyperaldosteronism, ascites, acne vulgaris, hirsutism, and female pattern hair loss. For hair loss, spironolactone works by blocking androgen receptors and reducing the production of testosterone and its potent metabolite, dihydrotestosterone (DHT), which are key players in androgenetic alopecia and other conditions influenced by androgens, such as hirsutism and acne.
Research underscores Spironolactone's efficacy, with studies highlighting positive outcomes in treating hirsutism and androgenic alopecia in women, demonstrating improvements in hair density and a reduction in hair shedding with few side effects.
The community reflects a variety of sentiments and experiences with spironolactone, particularly among women tackling hair loss. Members share stories of improved hair health and reduced shedding, often discussing its use in combination with other treatments like minoxidil to enhance outcomes. While many report positive effects, discussions also touch on the importance of monitoring for potential side effects and the need for a tailored approach under medical guidance. Community exchanges underscore spironolactone as a valued option in the broader treatment landscape for hair loss, especially for those seeking alternatives to more conventional therapies.
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2 resultsResearch
20 / 1000+ results![Treatment of Hirsutism With Spironolactone](/images/research/a5a6bb84-675f-4576-88bd-453c2fcb3b6d/small/34470.jpg)
research Treatment of Hirsutism With Spironolactone
research The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women
research A Novel Use of Spironolactone: Treatment of Hirsutism
research Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne
![Oral spironolactone therapy for female patients with acne, hirsutism or androgenic alopecia](/images/research/8eb48eac-d3ea-4a5c-a436-4058de9f6972/small/12388.jpg)
research Oral spironolactone therapy for female patients with acne, hirsutism or androgenic alopecia
![Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double Blind, Placebo-Controlled Trial1](/images/research/63e219b7-8d70-41ee-bcd4-b215251dcc5b/small/2277.jpg)
research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double Blind, Placebo-Controlled Trial1
![Side-Effects of Spironolactone Therapy in the Hirsute Woman](/images/research/5991856a-df83-4ac7-8311-1ace685fc3f2/small/34456.jpg)
research Side-Effects of Spironolactone Therapy in the Hirsute Woman
![Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women*](/images/research/ec5a95cb-e8f9-4c53-a2b0-b21abf5efc7e/small/21147.jpg)
research Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women*
![A case series of 20 women with hidradenitis suppurativa treated with spironolactone](/images/research/3f1706bb-d39e-4a0b-a582-288003d81027/small/18643.jpg)
research A case series of 20 women with hidradenitis suppurativa treated with spironolactone
![Innovative use of spironolactone as an antiandrogen in the treatment of female pattern hair loss.](/images/research/5ce228cb-49b0-4eb6-b16f-42fd1ee0ae84/small/2968.jpg)
research Innovative use of spironolactone as an antiandrogen in the treatment of female pattern hair loss.
![Influence of spironolactone treatment on endothelial function in non-obese women with polycystic ovary syndrome](/images/research/dba72ad1-e3f5-47d6-a496-96acc1162c38/small/26186.jpg)
research Influence of spironolactone treatment on endothelial function in non-obese women with polycystic ovary syndrome
![The effect of spironolactone on genital skin 5α-reductase activity](/images/research/9637ce9b-6c66-456e-9bc2-e6c61eff1d7e/small/28306.jpg)
research The effect of spironolactone on genital skin 5α-reductase activity
![Antiandrogen therapy with spironolactone for the treatment of hidradenitis suppurativa](/images/research/dd04d4c5-850f-4dbb-b2c6-d93350b3825b/small/13421.jpg)
research Antiandrogen therapy with spironolactone for the treatment of hidradenitis suppurativa
![A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism](/images/research/bc327576-9ade-4e1c-b850-ddfd975a8b38/small/2529.jpg)
research A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism
![Spironolactone in combination drug therapy for unresponsive hirsutism](/images/research/e8582e2f-e658-4d20-bb91-d33970a3c641/small/34465.jpg)
research Spironolactone in combination drug therapy for unresponsive hirsutism
research Spironolactone Therapy for Hirsutism in a Hyperandrogenic Woman
![Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19](/images/research/8688a347-6f22-4979-947c-f681cb69a3a8/small/17431.jpg)
research Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
![Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne](/images/research/a1535009-5c40-4d1b-b897-3b61f0f07d59/small/28148.jpg)
research Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne
research THE EFFECT OF SPIRONOLACTONE ON HIRSUTISM AND FEMALE ANDROGEN METABOLISM
![Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone](/images/research/62c396ef-064d-407f-9acf-7ff78073765a/small/15406.jpg)