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    Spironolactone

    also Aldactone

    Spironolactone, sold under the brand name Aldactone among others, is classed as a diuretic medication. It can be used to treat fluid build-up due to liver disease or kidney disease. It is also used to reduce risk of disease progression, hospitalization, and death due to some types of heart failure. Other uses include acne and excessive hair growth in women, low blood potassium that does not improve with supplementation, high blood pressure that is difficult to treat, and early puberty in boys. It is also used to block the effects of testosterone as a part of feminizing hormone therapy. Spironolactone is usually available in tablets, taken by mouth, though topical forms are also available.

    Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

    Research 10

    1. Efficacy and safety of oral spironolactone for female pattern hair loss in premenopausal women: a randomized, double-blind, placebo-controlled, parallel-group pilot study International Journal of Women’s Dermatology · 2025
    2. Safety and tolerability of combination oral spironolactone and low-dose oral minoxidil for hair loss in adult females: A retrospective cohort study Journal of the American Academy of Dermatology · 2026
    3. Clinical and Trichoscopic Evaluations of Topical Finasteride 1%, Topical Spironolactone 5%, and Minoxidil 5% in Female Pattern Hair Loss Treatment Dermatology Practical & Conceptual · 2025
    4. Safety Considerations and Monitoring in Patients Treated with Systemic Medications for Acne Dermatologic Clinics · 2016 · 10 citations
    5. Evaluation of the Efficacy and Safety of Topical Spironolactone versus Topical Minoxidil in the Treatment of Female Pattern Hair Loss: A Comparative, Clinical, and Trichoscopic Study International Journal of Trichology · 2025
    6. Supplementary Materials for Safety and tolerability of combination oral spironolactone and low-dose oral minoxidil for hair loss in adult females: A retrospective cohort study Mendeley Data · 2026
    7. Spironolactone versus Bicalutamide for Female Pattern Hair Loss: A 24-Month Unicenter Retrospective Comparative Study of Effectiveness and Safety Dermatology and Therapy · 2026
    8. Efficacy Of Hormonal Therapy Vs Non-Hormonal Therapy in Female Pattern Hair Loss (FPHL): A Systematic Review International Journal of Medicine in Developing Countries · 2026
    9. Low Risk of Hypotension in Women Treated with Spironolactone for Hair Loss Dermatology Practical & Conceptual · 2025
    10. Efficacy of Low-Dose Spironolactone for Hair Loss in Women. PubMed · 2024
    All research on Spironolactone →

    Community 10

    1. If i add a little daily dose of spironolactone (25 mg a day) would the improvement to my hair loss be significant? and also how likely is it to give me unwanted effects? My current regimen is 6 days / week oral Finasteride, 1 day / week oral Dutasteride and twice a day minoxidil foam Reddit · 29 Aug 2026
    2. Avodart (dut) side effects tracking Reddit · 15 Nov 2022
    3. Any men here taking oral spironolactone? Reddit · 16 Jul 2026
    4. Doctor prescribed me Spironolactone instead of Finasteride Reddit · 15 Sept 2026
    5. I am a 30 yo woman and having been taking oral minoxidil and spirinolactone... nothing. What gives? Reddit · 24 Apr 2026
    6. Topical spironolactone question Reddit · 18 Apr 2023
    7. Dose of oral spironolactone for males to stop hairloss when 5ari blockers not working, any idea Reddit · 5 Apr 2026
    8. spironolactone vs dutasteride Which one is more effective? Reddit · 24 Mar 2026
    9. What combination should I do of min, fin and spironolactone - woman Reddit · 16 Jan 2026
    10. Are there any males here that use (or have used) topical spironolactone? Reddit · 2 Jan 2026
    All community posts on Spironolactone →