Spironolactone

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    • Aldactone

    TLDR powerful topical and oral anti-androgen used mostly by women

    🛒 Where to find Spironolactone

    Tracking 1 topical product by companies like Minoxidil Express. View product »

    Spironolactone is a versatile medication, traditionally used as a diuretic for treating conditions like hypertension and heart failure, but it also plays a significant role in dermatology and hair loss treatment. Known as a mineralocorticoid receptor antagonist and potassium-sparing diuretic with powerful anti-androgenic properties, it is also used for primary hyperaldosteronism, ascites, acne vulgaris, hirsutism, and female pattern hair loss. For hair loss, spironolactone works by blocking androgen receptors and reducing the production of testosterone and its potent metabolite, dihydrotestosterone (DHT), which are key players in androgenetic alopecia and other conditions influenced by androgens, such as hirsutism and acne.

    Research underscores Spironolactone's efficacy, with studies highlighting positive outcomes in treating hirsutism and androgenic alopecia in women, demonstrating improvements in hair density and a reduction in hair shedding with few side effects.

    The community reflects a variety of sentiments and experiences with spironolactone, particularly among women tackling hair loss. Members share stories of improved hair health and reduced shedding, often discussing its use in combination with other treatments like minoxidil to enhance outcomes. While many report positive effects, discussions also touch on the importance of monitoring for potential side effects and the need for a tailored approach under medical guidance. Community exchanges underscore spironolactone as a valued option in the broader treatment landscape for hair loss, especially for those seeking alternatives to more conventional therapies.

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      community Spironolactone and pregnancy planning

      in Female  2 upvotes 5 months ago
      A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

      community spironolactone pills to topical

      in Research/Science  6 upvotes 5 months ago
      Crushing spironolactone pills and combining them with minoxidil for topical application may be effective for hair loss, with the addition of finasteride suggested. Adding rosemary and peppermint oils can help mask the unpleasant smell.

      community Does the effect of spironolactone on androgenetic alopecia really weaken over time?

      in Female  4 upvotes 8 months ago
      Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.

      community Spironolactone VS dutasteride for female pattern hair loss

      in Treatment  7 upvotes 1 year ago
      Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.

      community Spironolactone, what do you think?

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      A user is considering Spironolactone for hair loss but is advised against it due to its effects on testosterone. Instead, they are recommended to try finasteride at 18 and consider dutasteride if needed.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 1 year ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community Spironolactone topically with a try ?!

      in Research/Science  1 upvotes 1 year ago
      A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.

      community Spironolactone or bicalutamide prescription

      in Treatment  4 upvotes 2 years ago
      The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.

      community medication for hair loss spironolactone

      in Female  3 upvotes 2 years ago
      41-year-old female experienced slow hair thinning, took finasteride for a year, then switched to spironolactone. Irregular periods occurred, seeking advice on long-term side effects and considering a third medication.

      community Spironolactone for hair loss??

      in Product  6 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.

      community Topical spironolactone — how much do you apply?

      in Female  3 upvotes 3 months ago
      A user with androgenetic alopecia is using 8 ml of 1.4% topical spironolactone solution daily but is unsure if this amount is excessive, as 2 ml is more typical. They seek advice on the appropriate amount to apply.

      community Topical spironolactone — how many ml do you apply?

      in Female  7 upvotes 4 months ago
      The conversation discusses the use of topical spironolactone for hair loss, with the original poster applying 8 ml daily but learning that 2 ml is recommended. It also touches on hair transplants and the role of DHT sensitivity in hair loss, emphasizing individual differences in treatment outcomes.

      community How effective is topical spironolactone for androgenic alopecia?

      in Female  1 upvotes 6 months ago
      Topical spironolactone is discussed as a potential treatment for androgenic alopecia, with the user seeking feedback on its effectiveness. Minoxidil, finasteride, and other treatments like microneedling and keto shampoo are mentioned as alternatives.

      community Combining spironolactone with koshine?

      in Chat 1 year ago
      Combining spironolactone with koshine might enhance the effect of blocking androgen receptors for hair loss treatment. The user suggests adding crushed spironolactone pills to koshine.

      community Topical Spironolactone 5% effectiveness

      in Product  2 upvotes 1 year ago
      Topical spironolactone 5% is being discussed for its effectiveness in treating hair loss, specifically receding temples. The user is inquiring if it works similarly to finasteride as a testosterone blocker.
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