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GlossarySpironolactone

medication that blocks hormones to treat hair loss and acne

Spironolactone, also known by the brand name Aldactone, is a medication primarily used as a diuretic and antihypertensive. It works by blocking the action of aldosterone, a hormone that regulates salt and water balance in the body. In addition to its primary uses, it is also prescribed off-label for conditions like acne and hirsutism (excessive hair growth) due to its anti-androgenic properties, and it can be beneficial in treating certain types of hair loss, such as androgenetic alopecia.

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community Spironolactone VS dutasteride for female pattern hair loss

in Treatment 7 upvotes 3 months ago

Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.

community Spironolactone, what do you think?

in Finasteride/Dutasteride 4 upvotes 4 months ago

A user is considering Spironolactone for hair loss but is advised against it due to its effects on testosterone. Instead, they are recommended to try finasteride at 18 and consider dutasteride if needed.

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 8 months ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

community Spironolactone topically with a try ?!

in Research/Science 1 upvotes 10 months ago

A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.

community Spironolactone or bicalutamide prescription

in Treatment 4 upvotes 1 year ago

The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.

community medication for hair loss spironolactone

in Female 3 upvotes 1 year ago

41-year-old female experienced slow hair thinning, took finasteride for a year, then switched to spironolactone. Irregular periods occurred, seeking advice on long-term side effects and considering a third medication.

community Spironolactone for hair loss??

in Product 6 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.

community spironolactone vs bicalutamide What is the difference between them for androgenic alopecia for women?

in Female 7 upvotes 2 years ago

Hair loss discussion involves spironolactone and bicalutamide for women's androgenic alopecia. Focus on effectiveness and side effects.

community Combining spironolactone with koshine?

in Chat 4 months ago

Combining spironolactone with koshine might enhance the effect of blocking androgen receptors for hair loss treatment. The user suggests adding crushed spironolactone pills to koshine.

community Topical Spironolactone 5% effectiveness

in Product 2 upvotes 5 months ago

Topical spironolactone 5% is being discussed for its effectiveness in treating hair loss, specifically receding temples. The user is inquiring if it works similarly to finasteride as a testosterone blocker.

community Topical Spironolactone 2.5% MONOTHERAPY x 1 year (MALE)- Nothing else

in Progress Pictures 10 upvotes 7 months ago

A male in his early 40s, who experienced side effects from finasteride, used 2.5% topical spironolactone for one year with no side effects but minimal regrowth. He plans to try a 5% spironolactone solution next.

community How effective is topical spironolactone for men ?

in Product 6 upvotes 11 months ago

Topical spironolactone's effectiveness for men is discussed, comparing it to finasteride. Users share experiences and opinions on its use for hair loss treatment.

community Topical Spironolactone 2.5% MONOTHERAPY x 5 months (MALE)- Nothing else

in Progress Pictures 16 upvotes 1 year ago

A man in his 40s treating his slow balding with a daily regimen of 2.5% spironolactone topical solution and Piroctone Olamine Shampoo. Despite initial hair shedding, he experienced no side effects and plans to continue the treatment for at least a year.

community Tricho test suggested topical spironolactone. Any experience with it?

in Treatment 7 upvotes 1 year ago

The conversation is about a person experiencing hair loss, using topical minoxidil for 8 years, now at Norwood scale 3, and considering topical spironolactone and oral minoxidil after a tricho test recommendation. They are seeking others' experiences with topical spironolactone.

community Topical spironolactone question

in Product 2 upvotes 1 year ago

User started using topical spironolactone on scalp and face, experienced fever feeling and sluggishness. Asks if side effects are normal or systemic.

community Starting Spironolactone, any ladies in here with experience or success?

in Female 56 upvotes 1 year ago

A female user starting Spironolactone treatment for thinning hair, and others sharing their experiences with Minoxidil and oral/sublingual Minoxidil as treatments.

community where does the renewed spironolactone hype come from?

in Research/Science 9 upvotes 2 years ago

Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

community Topical spironolactone - anti androgen

in Research/Science 10 upvotes 2 years ago

User asks about topical spironolactone experience. Two studies show it as promising anti-androgen treatment, with 5% cream available on Minoxidilmax website.

community How effective is spironolactone?

in Transgender 6 upvotes 2 years ago

A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hair loss, despite being aware of its serious side effects.

community topical spironolactone as alternative to RU to reduce scalp testosterone in men

in Treatment 7 upvotes 2 years ago

User tried topical fin, dut, min, tret, hydrocortisone, microneedling, nizoral, collagen, propidren supplements, and laser helmet for hair loss with slow progress. They ask if topical spironolactone is a safer, effective alternative to RU for suppressing testosterone and treating hair loss in men.

community Experience with Spironolactone?

in Female 7 upvotes 3 years ago

Spudlady asks about experiences with spironolactone for hair loss. She has lost hair due to stress and seeks ways to stop shedding.

community According to one study, topical spironolactone is more effective than topical finasteride for both men women.

in Treatment 13 upvotes 3 years ago

Topical spironolactone is more effective than topical finasteride for treating hair loss in both men and women. Oral spironolactone can affect testosterone, but the topical form doesn't impact the endocrine system.

community Topical spironolactone from MinoxidilMax

in Treatment 7 upvotes 3 years ago

Hair loss discussion includes topical spironolactone treatment, used 1-2 times daily for 2 weeks with no changes yet. Minoxidil and Propecia caused nasty side effects for the user.

community Spironolactone Update

in Female 11 upvotes 7 years ago

A woman's experience with Spironolactone as treatment for female pattern hair loss, including the effects of increasing dosage and her doctor's recommendation to try finasteride if no results are seen after 6 months. Other users have also shared their experiences with using finasteride for this condition.

community Topical Spironolactone Mixing Guide

6 upvotes 7 years ago

A user shared a guide for mixing a topical spironolactone solution for hair loss, using ingredients like spironolactone tablets, ethyl alcohol, and propylene glycol. They compared it to the S5 cream, finding their homemade solution more practical and cost-effective.

community Finasteride 5mg & Spironolactone 100mg

in Female 2 upvotes 3 weeks ago

A 20-year-old female is using finasteride 5mg and spironolactone 100mg for severe hirsutism and is experiencing minor side effects like water weight loss and irregular periods. She is concerned about potential future side effects and hair regrowth on her scalp.

community Began MTF HRT (estradiol/spironolactone) at 39. The images are about 5 months apart. I haven't started minoxidil yet as I'm waiting to see how far I can get with suppressing T alone. I'm guarded, but hopeful I won't be needing wigs eternally.

in Transgender 7 upvotes 5 months ago

A transgender individual began MTF HRT with estradiol and spironolactone at 39 and is monitoring hair regrowth before starting minoxidil. They are hopeful about not needing wigs permanently.

community At what dose did Spironolactone really start working?

in Female 2 upvotes 8 months ago

A user is asking women with androgenic alopecia about the effective dose of spironolactone for hair regrowth, mentioning they've been on 100 mg for a year with minimal results and considering increasing the dose. The conversation focuses on the effectiveness of spironolactone for hair loss treatment.

community Homemade topical spironolactone

in Research/Science 25 upvotes 2 years ago

The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

community bicalutamide or spironolactone for fphl

in Female 6 upvotes 2 years ago

Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.