Topical spironolactone — how many ml do you apply?
    6/20/2025

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💧 topical spironolactone (topical) 1.4% 1x daily 1 month
    the tone is 😐 neutral with some growth results.

    Other terms

    The conversation discusses the use of topical spironolactone for hair loss, with the original poster applying 8 ml daily but learning that 2 ml is recommended. It also touches on hair transplants and the role of DHT sensitivity in hair loss, emphasizing individual differences in treatment outcomes.
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    5 / 5 results

      community I wish I were a man so bad. Life is cruel

       225 upvotes 6 months ago
      A woman with androgenetic alopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.

      community Are any of you using topical spironolactone ?

      in Treatment  4 upvotes 1 year ago
      The user is using topical dutasteride, minoxidil, and spironolactone for hair loss, with positive results after adding spironolactone. Another user takes oral spironolactone, dutasteride, and finasteride, noting decreased libido but no major side effects.

      community Don't fall for the fear mongering bros

       1533 upvotes 1 year ago
      Hair loss treatments discussed include finasteride, minoxidil, spironolactone, and estradiol, with concerns about side effects like sexual dysfunction and feminization. Some users prefer hair transplants or shaving over medication due to potential side effects.

      community How much DHT causes hair loss ?

      in Finasteride/Dutasteride  2 upvotes 10 months ago
      The user is taking 2.5 mg dutasteride and 5% minoxidil but is not seeing hair regrowth, and is considering adding RU58841. They are experiencing fatigue and low MCV/MCH, possibly related to dutasteride, and are advised to be patient, consider microneedling, and check for iron deficiency.

    Related Research

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      December 2025 in “International Journal of Innovative Technologies in Social Science”
      This review outlines that minoxidil (topical and oral) and 5α-reductase inhibitors are the most effective treatments for androgenetic alopecia, with additional therapies like platelet-rich plasma and hair transplantation enhancing results, emphasizing the need for individualized, combination approaches.
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      Androgenetic Alopecia: An Update

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      July 2023 in “JAAD International”
      This study describes androgenetic alopecia as a common non-scarring hair loss condition primarily influenced by genetic factors and androgen sensitivity, notably impacting psychosocial well-being, especially in females and younger males seeking treatment.
      Managing Patterned Hair Loss – A Hair Raising Task!

      research Managing patterned hair loss – a hair raising task!

      October 2021 in “Cosmoderma”
      This review summarizes existing knowledge on diffuse and patterned alopecia, emphasizing recent advancements in treatment beyond FDA-approved options, but it reports no new clinical findings.