A Case Series of 20 Women with Hidradenitis Suppurativa Treated with Spironolactone

    June 2015 in “ Australasian Journal of Dermatology ”
    Andrew Lee, Gayle Fischer
    Image of study
    TLDR Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.
    In a retrospective case series from 2015, 20 women with hidradenitis suppurativa were treated with spironolactone. The patients had a mean age of 31.7 years and disease onset at 24.6 years. At a 3-month follow-up, 85% showed improvement, with 55% achieving complete disease suppression. The treatment was well-tolerated, and the study concluded that spironolactone is a useful and low-cost first-line treatment for HS in women. The study also found no added benefit from combining spironolactone with tetracycline or oral contraceptives, and suggested that 2 mg of cyproterone acetate may be less effective than 100 mg of spironolactone. Despite its limitations, such as the small sample size, the study supported the use of anti-androgen therapy for HS.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 358 results

      community Spironolactone VS dutasteride for female pattern hair loss

      in Treatment  7 upvotes 3 months ago
      Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.

      community Spironolactone, what do you think?

      in Finasteride/Dutasteride  4 upvotes 4 months ago
      A user is considering Spironolactone for hair loss but is advised against it due to its effects on testosterone. Instead, they are recommended to try finasteride at 18 and consider dutasteride if needed.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 8 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community Spironolactone topically with a try ?!

      in Research/Science  1 upvotes 10 months ago
      A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.

      community Spironolactone or bicalutamide prescription

      in Treatment  4 upvotes 1 year ago
      The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.

      community medication for hair loss spironolactone

      in Female  3 upvotes 1 year ago
      41-year-old female experienced slow hair thinning, took finasteride for a year, then switched to spironolactone. Irregular periods occurred, seeking advice on long-term side effects and considering a third medication.

    Related Research

    4 / 4 results