Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia

    Rehab Nabil Shamma, Mona Hassan Aburahma
    Studysummary This study suggests that spironolactone-loaded nanostructured lipid carriers could enhance follicular delivery and offer a more localized treatment for androgenic alopecia, potentially reducing systemic side effects.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. Female Pattern Alopecia: Current Perspectives International Journal of Women's Health · 2013
    2. Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss PubMed · 2010
    3. Transcutol-Containing Vesicles for Topical Delivery of Minoxidil Journal of Drug Targeting · 2010
    4. Successful Treatment of Female-Pattern Hair Loss with Spironolactone in a 9-Year-Old Girl Australasian Journal of Dermatology · 2009
    5. Hormones and the Pilosebaceous Unit Dermato-endocrinology · 2009
    6. Follicular Transport Route: Research Progress and Future Perspectives European journal of pharmaceutics and biopharmaceutics · 2009
    7. Beneficial Effect of Spironolactone on Androgenic Alopecia Clinical Endocrinology · 1997
    8. Description of the Intrafollicular Delivery of Large Molecular Weight Molecules to Follicles of Human Scalp Skin In Vitro Journal of Pharmaceutical Sciences · 1997
    9. Oral Spironolactone Therapy for Female Patients with Acne, Hirsutism, or Androgenic Alopecia British Journal of Dermatology · 1985

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    2. Sensitive Scalp: An Epidemiologic Study in Patients with Hair Loss Dermatology Reports · 2022