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GlossaryNanostructured Lipid Carriers (NLCs)

advanced drug delivery systems using solid and liquid lipid nanoparticles

Nanostructured Lipid Carriers (NLCs) are advanced drug delivery systems composed of a blend of solid and liquid lipids, forming nanoparticles that can encapsulate active ingredients. These carriers enhance the stability, bioavailability, and controlled release of drugs, making them particularly useful in medical and cosmetic applications, including treatments for hair loss and skin conditions.

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Nanostructured Lipid Carriers Composed of Argan Oil: A Potential Novel Vehicle for Caffeine Delivery to Stratum Corneum and Hair Follicles

research Nanostructured Lipid Carriers Composed of Argan Oil: A Potential Novel Vehicle for Caffeine Delivery to Stratum Corneum and Hair Follicles

January 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Argan oil-based nano carriers could potentially deliver caffeine to hair follicles to treat hair loss.

research Effect of Physical Stimuli on Hair Follicle Deposition of Clobetasol-Loaded Lipid Nanocarriers

52 citations , January 2020 in “Scientific Reports”

NLCs with manual massage greatly improve clobetasol delivery to hair follicles.

research Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia

89 citations , November 2014 in “International Journal of Nanomedicine”

Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.

Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata

research Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata

59 citations , October 2012 in “Pharmaceutical Research”

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery

research Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery

47 citations , April 2017 in “European Journal of Pharmaceutics and Biopharmaceutics”

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

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community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 2 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Melatonin a possible tool to help fight AGA hair loss.

in Research/Science 50 upvotes 4 years ago

Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.