A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women

    January 1995 in “ The Journal of Clinical Endocrinology and Metabolism ”
    I. Lane Wong, R. V. Morris, Leland Chang … Roger A. Lobo
    Studysummary This study observed that finasteride and spironolactone both led to a similar significant, but limited, improvement in hirsutism despite their differing effects on androgen levels.
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    Research cited in this study 7

    1. Androgen Conjugates: Physiology and Clinical Significance Endocrine reviews · 1993
    2. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992
    3. Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque The Journal of Clinical Endocrinology and Metabolism · 1992
    4. The Clinical Development of a 5α-Reductase Inhibitor, Finasteride The Journal of Steroid Biochemistry and Molecular Biology · 1990
    5. The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women Fertility and sterility · 1985
    6. Treatment of Hirsutism With Spironolactone JAMA · 1982
    7. A Novel Use of Spironolactone: Treatment of Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1980

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    2. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992
    3. Bioactive and Peripheral Androgens in Prepubertal Simple Hypertrichosis Clinical Endocrinology · 1990