Central 5-Alpha Reduction of Testosterone Is Required for Testosterone's Inhibition of the Hypothalamo-Pituitary-Adrenal Axis Response to Restraint Stress in Adult Male Rats

    July 2013 in “ Brain Research ”
    Robert J. Handa, Andrea E. Kudwa, Nina C. Donner … Roger Brown
    Studysummary Testosterone needs to be converted to DHT to reduce stress response in male rats.
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    Research cited in this study 1

    1. Increase in Testosterone Metabolism in the Rat Central Nervous System by Formalin-Induced Tonic Pain Pharmacology Biochemistry and Behavior · 2002

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