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GlossaryAdrenocorticotropic Hormone (ACTH)

hormone stimulating adrenal glands to release cortisol

Adrenocorticotropic Hormone (ACTH), also known as corticotropin, is a hormone produced by the pituitary gland that stimulates the adrenal glands to release cortisol, a crucial stress hormone. This hormone plays a key role in regulating metabolism, immune response, and stress, and its imbalance can lead to conditions such as Cushing's disease or Addison's disease.

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The Diagnosis of Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Based on Serum Basal or Post-ACTH Stimulation 17-Hydroxyprogesterone Can Lead to False-Positive Diagnosis

research The Diagnosis of Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Based on Serum Basal or Post-ACTH Stimulation 17-Hydroxyprogesterone Can Lead to False-Positive Diagnosis

25 citations , September 2015 in “Clinical Endocrinology”

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

research Melanocortin Receptor Type 2 (MC2R, ACTH Receptor) Expression in Patients with Alopecia Areata

22 citations , June 2010 in “Experimental Dermatology”

Lower MC2R expression may contribute to alopecia areata.

research Is It Getting in the Hair? Cortisol Concentrations in Native, Regrown, and Segmented Hairs of Cattle and Pigs After Repeated ACTH Administrations

19 citations , June 2020 in “General and comparative endocrinology”

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

research Adrenocorticotropic Hormone (ACTH) But Not Alpha-Melanocyte Stimulating Hormone (α-MSH) as a Mediator of Adrenalectomy-Induced Hair Growth in Mink

16 citations , April 1998 in “Journal of Investigative Dermatology”

ACTH promotes hair growth in mink, but α-MSH does not.

research ACTH as First Line Treatment for Acute Calcium Pyrophosphate Crystal Arthritis in 14 Hospitalized Patients

14 citations , June 2013 in “Joint Bone Spine”

ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.

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community Result of my cortisol, prolactin, testosterone, ACTH blood test,

in Update 4 weeks ago

OP is using 5% minoxidil and a foligain supplement for hair loss, with blood test results showing high cortisol levels. OP is considering starting finasteride, while another user shares their experience with finasteride and hair loss challenges due to malabsorption issues.

community 2 years on treatment (stack update)

in Progress Pictures 466 upvotes 9 months ago

A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

community How does hair loss and recovery work?

in Chat 12 upvotes 1 year ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

in Research/Science 11 upvotes 11 months ago

Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.