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GlossaryCushing's syndrome

condition caused by excessive cortisol, leading to weight gain and skin changes

Cushing's syndrome, also known as hypercortisolism, is a condition characterized by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. This can result from taking corticosteroid medications or from the body producing too much cortisol due to tumors in the pituitary or adrenal glands. Symptoms include weight gain, particularly around the abdomen and face, thinning skin, easy bruising, and in some cases, hair loss or excessive hair growth.

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research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)

4025 citations, January 2004 in “Human Reproduction”

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

research Complications of Cushing's Syndrome: State of the Art

374 citations, July 2016 in “The Lancet. Diabetes & endocrinology”

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

research Studying the Correlation of Renin-Angiotensin-System Components and Insulin Resistance in Polycystic Ovary Syndrome

12 citations, March 2013 in “Gynecological Endocrinology”

The study found a significant link between the renin-angiotensin system and insulin resistance in women with polycystic ovary syndrome.

research Androgen Excess in Women: Experience with Over 1000 Consecutive Patients

947 citations, February 2004 in “The Journal of Clinical Endocrinology and Metabolism”

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

research The Role of High Serum Uric Acid Levels in Androgenic and Non-Androgenic Polycystic Ovarian Syndrome Patients

2 citations, October 2021 in “Clinical Epidemiology and Global Health”

High uric acid levels are more common in PCOS patients, especially those with androgenic PCOS, and are linked with increased cardiovascular risk and other metabolic issues.

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community C’est terrible - at my wits end

in Female 445 upvotes 9 months ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Starting Spironolactone, any ladies in here with experience or success?

in Female 56 upvotes 1 year ago

A female user starting Spironolactone treatment for thinning hair, and others sharing their experiences with Minoxidil and oral/sublingual Minoxidil as treatments.

community 1.5 years on fin/min progress pics, thoughts would be great!

in Progress Pictures 69 upvotes 3 years ago

A 42-year-old male shared his 1.5-year hair regrowth progress using 1.25mg finasteride daily and regular doses of minoxidil twice a day, and recently started using the Derminator 2. He also mentioned his battle with cancer and Cushing's syndrome, which affected his weight and hair.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 10 months ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Breezula will hit the market in 2026, Cosmo Pharmaceuticals statement!

in Product 51 upvotes 5 months ago

Breezula, a hair loss treatment, is expected to cost around $100 a month and is anticipated to be released in 2026. The effectiveness of Breezula is debated, with some suggesting it loses effectiveness over time and others arguing it maintains hair compared to baseline.

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