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Glossary Dexamethasone Suppression Test

measures cortisol response to synthetic glucocorticoid dexamethasone

The Dexamethasone Suppression Test (DST) is a diagnostic procedure used to assess adrenal gland function by measuring how cortisol levels in the blood respond to an injection of dexamethasone, a synthetic glucocorticoid. It is commonly used to diagnose conditions like Cushing's syndrome, where the body produces too much cortisol.

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research Hyperandrogenic eumenorrheic NON-PCOS women versus women with PCOS after the GnRH-agonist stimulation test preceded by suppression of adrenal steroidogenesis with dexamethasone

1 citations , September 2024 in “Journal of Clinical & Translational Endocrinology”

This study found that women with polycystic ovary syndrome have more pronounced metabolic alterations and higher androgen levels compared to women with eumenorrheic hyperandrogenism, suggesting EuHyperA may be a milder form of PCOS.

research Differential Suppression of Testosterone and Estradiol in Hirsute Women With the Superactive Gonadotropin-Releasing Hormone Agonist Leuprolide*

49 citations , October 1988 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that low doses of leuprolide effectively suppressed serum estradiol and LH response, while higher doses were needed to suppress testosterone and reduce hair growth in hirsute women.

research Co-secretion of testosterone and cortisol by a functional adrenocortical oncocytoma

16 citations , August 2007 in “Histopathology”

This case report describes a functional adrenocortical oncocytoma that co-secreted testosterone and cortisol.

research Differential Diagnosis of Hyperandrogenism in Women with Polycystic Ovary Syndrome

35 citations , March 2012 in “Experimental and Clinical Endocrinology & Diabetes”

This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.