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Glossary Oral Prednisolone

corticosteroid medication taken orally to reduce inflammation

Oral Prednisolone is a corticosteroid medication taken by mouth to reduce inflammation and suppress the immune system. It is commonly used to treat conditions such as asthma, allergies, and autoimmune diseases, including certain types of alopecia.

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Research

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research Placebo-controlled oral pulse prednisolone therapy in alopecia areata

141 citations , February 2005 in “Journal of the American Academy of Dermatology”

In this study, oral prednisolone pulse therapy led to significant hair regrowth in some patients with extensive alopecia areata, whereas no improvement was seen in the placebo group.

research Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus

16 citations , October 2013 in “Anais Brasileiros de Dermatologia”

In this case report, an elderly woman with erosive pustular dermatosis of the scalp showed complete closure of eroded areas after treatment with prednisone and topical tacrolimus, resulting in stable scarring alopecia.

research ALOPECIA UNIVERSALIS TREATED WITH ORAL CYCLOSPORINE A AND PREDNISOLONE: IMMUNOLOGIC STUDIES

26 citations , July 1992 in “International Journal of Dermatology”

In this study, treating refractory alopecia universalis with low-dose cyclosporine A and prednisolone improved symptoms, with no recurring alopecia six months post-treatment and enhancements in immunologic function.

research Comparative Efficacy Study Combination of Oral Methotrexate and Prednisolone versus Oral Methotrexate in Patients with Lichen Planopilaris

4 citations , January 2022 in “Dermatology Research and Practice”

In this study, methotrexate therapy with or without corticosteroids showed similar efficacy and safety in treating patients with lichen planopilaris, with no significant differences in the primary outcome or adverse effects between the two groups.

research Alteration of serum and tissue tumor necrosis factor alpha levels: A possible mechanism of action of oral pulse steroids in the treatment of alopecia areata

5 citations , October 2018 in “Journal of Cosmetic Dermatology”

This study found that oral pulse steroids significantly reduced serum and tissue levels of TNF-α in patients with alopecia areata, correlating with clinical improvement.

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community Before and After oral 2.5 mg Minoxidil (~3 months), no finasteride

in Progress Pictures 1 upvotes 11 months ago

The user experienced significant hair improvement after using 2.5 mg oral Minoxidil for about three months, without finasteride, and noticed reduced shedding and darker hair. They also improved their diet and took vitamins, which may have contributed to the results.

community 18 months of oral Minoxidil, 5 months of Finasteride.

1155 upvotes 1 year ago

The user experienced significant hair regrowth using oral Minoxidil (5mg daily) for 18 months and Finasteride (1mg daily) for 5 months, with minimal side effects. The combination stopped hair loss and improved hair thickness, although a hair transplant is still considered for a receded hairline.

community Got a hair transplant a few days ago and my forehead is so swollen

in Transplants 212 upvotes 1 year ago

Swelling after a hair transplant is normal and can be reduced with ice packs, head elevation, and possibly corticosteroids. The user had a no-shave FUE procedure and is using oral finasteride and minoxidil.

community Dutasteride High Libido. How come we don't talk about this?

in Finasteride/Dutasteride 210 upvotes 1 year ago

Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

community Why do so many people trash on finasteride?

in Chat 247 upvotes 1 year ago

Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? No study has compared topical and oral estradiol for hair loss, and estradiol applied to skin is still absorbed into the blood. Either form needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

learn Pyrilutamide

Is pyrilutamide a safer alternative to oral antiandrogens like finasteride? Pyrilutamide (KX-826) is an unapproved, investigational topical antiandrogen whose safety data come from short-term sponsor announcements, not peer-reviewed studies. No study has compared it with finasteride, so there is no evidence that it is safer.

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