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Glossary Oral Lichen Planus

chronic inflammatory condition affecting mouth's mucous membranes

Oral Lichen Planus (OLP) is a chronic inflammatory condition that affects the mucous membranes inside the mouth, leading to white, lacy patches, red swollen tissues, or open sores. It can cause discomfort, pain, and difficulty eating or speaking, and while the exact cause is unknown, it is believed to be an autoimmune disorder where the body's immune system attacks the cells of the oral mucosa.

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Research

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research Efficacy of Platelet-Rich Plasma Therapy in Oral Lichen Planus: A Systematic Review

26 citations , April 2023 in “Medicina”

This systematic review suggests that platelet-rich plasma may significantly improve symptoms in oral lichen planus with effects comparable to corticosteroids, although more research is needed to confirm these findings.

research Lipid Profile and Metabolic Syndrome Status in Patients with Oral Lichen Planus, Oral Lichenoid Reaction and Healthy Individuals Attending a Dental College in Northern India - A Descriptive Study

17 citations , January 2014 in “Journal of Clinical and Diagnostic Research”

This study found that patients with oral lichen planus and oral lichenoid reactions have higher levels of serum cholesterol and LDL-C than healthy individuals, suggesting a potential elevated risk for cardiovascular disease.

research Oral Lichen Planus

7 citations , July 2013 in “InTech eBooks”

This article describes the various presentations of oral lichen planus and notes it often requires topical or systemic immunosuppressive treatment for associated discomfort, but it reports no new clinical results.

research Bullous Lichen Planus treated with Oral Minipulse Therapy: A Rare Case Report

4 citations , January 2014 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH”

This article details various skin and oral lesions through illustrative figures but does not present new research results.

research Oral lichen planus preceding concomitant lichen planopilaris

2 citations , June 2016 in “Oral Surgery Oral Medicine Oral Pathology and Oral Radiology”

This study reports the first known case of oral lichen planus preceding lichen planopilaris in a patient, highlighting a possible sequential relationship between the conditions.

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community Duta 2,5mg/day - No Progress - 28M

in Update 5 upvotes 1 year ago

A 28-year-old is experiencing hair loss despite using treatments like oral minoxidil, finasteride, and high-dose dutasteride (2.5 mg). They suspect lichen planus might be contributing to the issue and plan to continue treatment while monitoring progress.

community UPDATE - 7 months 2,5 dutatesteride

10 upvotes 1 year ago

The user continues to experience hair loss despite using dutasteride 2.5mg, minoxidil 5mg, and ciclopirox shampoo, and plans to reassess after one year. Others report similar issues with dutasteride, with some switching to finasteride or adding RU58841.

community What is the ultimate hair regrowth protocol

29 upvotes 1 year ago

The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community It's over- 8 months in & I've got 0 progress from Dutasteride

38 upvotes 7 months ago

The user tried Dutasteride, Finasteride, and Minoxidil for hair loss but saw no improvement after nearly two years, feeling frustrated and considering giving up. Other users suggested trying different dosages, oral Minoxidil, RU58841, or considering a hair transplant, while some noted that stabilization without regrowth is common.

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