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    GlossaryOral Lichen Planus

    chronic inflammatory condition affecting mouth's mucous membranes

    Oral Lichen Planus (OLP) is a chronic inflammatory condition that affects the mucous membranes inside the mouth, leading to white, lacy patches, red swollen tissues, or open sores. It can cause discomfort, pain, and difficulty eating or speaking, and while the exact cause is unknown, it is believed to be an autoimmune disorder where the body's immune system attacks the cells of the oral mucosa.

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      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

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      community I've tried everything and my hair is still thinning

      in Chat  6 upvotes 10 months ago
      The user has tried finasteride, oral minoxidil, iron supplements, vitamin D, and vitamin B12, but their hair is still thinning after 5 years. Another user suggested trying dutasteride.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community He used Dutasteride for 20 years. Interview

      in Treatment  109 upvotes 1 month ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

      community Male pattern baldness, and mental health

      in Finasteride/Dutasteride  331 upvotes 10 months ago
      A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.