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    GlossaryAdrenal-Dependent Hyperadrenocorticism

    condition where adrenal tumors cause excessive cortisol production

    Adrenal-Dependent Hyperadrenocorticism (ADH), also known as adrenal-dependent Cushing's syndrome, is a condition where the adrenal glands produce excessive amounts of cortisol due to a tumor in one or both adrenal glands. This overproduction of cortisol can lead to symptoms such as weight gain, thinning skin, hair loss, and high blood pressure.

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      a synthetic cortisol used for anti-inflammatory effects

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      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 6 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community 2 year regrowth minoxidil and finasteride

      in Progress Pictures  521 upvotes 5 months ago
      The user experienced significant hair regrowth over two years using topical minoxidil and oral finasteride, with no side effects from finasteride. Despite initial skepticism from others, the user confirmed the progress was not due to a hair transplant.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community My Theory Of Androgenic Alopecia

      in Research/Science  17 upvotes 2 weeks ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.