Update on Drugs Used to Treat Endocrine Diseases in Small Animals

September 2006 in “ The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice ”

Ellen N. Behrend

trilostane insulin glargine PZI porcine Lente transdermal methimazole progestins methimazole

Studysummary This article reviews new drug therapies for endocrine disorders, discussing specific treatments such as trilostane for hyperadrenocorticism and various insulins for diabetes mellitus, but it reports no new clinical findings. Our plain-language summary of this paper — not a Tressless recommendation.

The article reviewed new drug therapies for treating endocrine disorders in small animals, focusing on diseases of the pituitary, adrenal, parathyroid, thyroid glands, and the endocrine pancreas. It discussed the use of trilostane for hyperadrenocorticism, various forms of insulin (glargine, PZI, porcine Lente) for diabetes mellitus, transdermal methimazole for feline hyperthyroidism, and progestins for pituitary dwarfism.

View this study on sciencedirect.com →

Discuss this study in the Community →

Research cited in this study

3 / 3 results

research Trilostane Treatment of a Dog with Functional Adrenocortical Neoplasia

40 citations , March 2003 in “The journal of small animal practice/Journal of small animal practice”

In this case study, medical management with trilostane improved clinical signs and normalized serum chemistry in a dog diagnosed with adrenal-dependent hyperadrenocorticism over 80 weeks of treatment.

research Trilostane Treatment of 78 Dogs With Pituitary-Dependent Hyperadrenocorticism

149 citations , June 2002 in “Veterinary record/The veterinary record”

This study found that trilostane was effective in resolving symptoms such as polyuria and polydipsia in many dogs with pituitary-dependent hyperadrenocorticism, with significant hormone level reductions observed.

Results of Clinical Examinations, Laboratory Tests, and Ultrasonography in Dogs with Pituitary-Dependent Hyperadrenocorticism Treated with Trilostane

research Results of Clinical Examinations, Laboratory Tests, and Ultrasonography in Dogs with Pituitary-Dependent Hyperadrenocorticism Treated with Trilostane

116 citations , April 2002 in “American journal of veterinary research”

This study found trilostane to be an effective and generally safe treatment for improving symptoms in dogs with pituitary-dependent hyperadrenocorticism.