149 citations
,
June 2002 in “Veterinary record/The veterinary record” This study found that trilostane was effective in resolving symptoms such as polyuria and polydipsia in many dogs with pituitary-dependent hyperadrenocorticism, with significant hormone level reductions observed.
116 citations
,
April 2002 in “American journal of veterinary research” This study found trilostane to be an effective and generally safe treatment for improving symptoms in dogs with pituitary-dependent hyperadrenocorticism.
40 citations
,
October 2004 in “Veterinary Dermatology” In this study, trilostane treatment led to complete hair re-growth in 85% of Pomeranians and all miniature poodles with alopecia X within 4 to 8 weeks.
40 citations
,
March 2003 in “The journal of small animal practice/Journal of small animal practice” In this case study, medical management with trilostane improved clinical signs and normalized serum chemistry in a dog diagnosed with adrenal-dependent hyperadrenocorticism over 80 weeks of treatment.
36 citations
,
June 2003 in “The journal of small animal practice/Journal of small animal practice” This case report describes a domestic shorthaired cat with pituitary-dependent hyperadrenocorticism treated with trilostane, which improved clinical signs, but the cat later succumbed to renal failure due to a fungal urinary tract infection.