Prevalence of Systemic Hypertension and Control of Systolic Blood Pressure in a Cohort of 14 Dogs with Adrenal-Dependent Hypercortisolism During the First Year of Trilostane Treatment or After Adrenalectomy
February 2024
in “
Animals
”
Studysummary In this study, dogs with adrenal-dependent hypercortisolism showed a decrease in the prevalence of systemic hypertension from 79% to 25% after a year of trilostane treatment or adrenalectomy, with blood pressure normalization observed by three months post-surgery in hypertensive dogs.
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This study evaluated 14 dogs with adrenal-dependent hypercortisolism (ADH) to assess the prevalence and control of systemic hypertension (SH) during the first year of trilostane treatment or after adrenalectomy. Initially, 79% of the dogs were hypertensive (SBP ≥ 160 mmHg), but this decreased to 25% after 12 months. Both treatment methods effectively reduced hypertension, with trilostane-treated dogs showing significant reductions in SH and adrenalectomy-treated dogs normalizing SBP within three months post-surgery. The study underscores the importance of individualized treatment and ongoing monitoring for dogs with ADH.
