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    GlossaryAdrenal Hyperandrogenism

    overproduction of male hormones by adrenal glands

    Adrenal Hyperandrogenism, also known as Adrenal Androgen Excess, is a condition where the adrenal glands produce an abnormally high level of androgens, which are male sex hormones like testosterone. This can lead to symptoms such as excessive hair growth (hirsutism), acne, and irregular menstrual cycles in women, and can be associated with conditions like polycystic ovary syndrome (PCOS) or congenital adrenal hyperplasia (CAH).

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      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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      community This and ketoconazole 2% life changing

      in Ketoconazole  69 upvotes 2 years ago
      The post discusses the user's experience with hair loss treatment using finasteride, clobetasol propionate, and ketoconazole shampoo. The conversation warns about the potential side effects of clobetasol, a powerful topical steroid, and emphasizes its short-term usage.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 7 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community Thoughts about ORAL ketoconazole? (pills)

      in Ketoconazole 2 months ago
      Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

      community DHEA, the culprit behind DUPA ? Read this!

      in Research/Science  20 upvotes 2 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community Adrogens and Covid-19

      in Treatment  7 upvotes 5 years ago
      The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.