Thoughts about ORAL ketoconazole? (pills)
    1/14/2026

    From the encyclopedia
    Ketoconazole →

    antifungal with some anti-androgenic benefits, often used as a shampoo

    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💊 Ketoconazole (oral) 400 mg/day
    💊 Spironolactone (oral)
    the tone is 😞 negative.

    Other terms

    Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.
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    5 / 5 results

      community Almost 7 months of Topical Fin + Min

       345 upvotes 9 months ago
      A 24-year-old shared their 7-month progress using a topical solution of finasteride 0.1%, minoxidil 5%, and hydrocortisone butyrate 0.08%, along with ketoconazole shampoo, to treat hair loss, reporting no side effects and noticeable hair improvement. They also take vitamin D and biotin supplements, use a dermastamp, and manage Hashimoto's without thyroid medication.

      community What is the ultimate hair regrowth protocol

       29 upvotes 1 year ago
      The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

      community Do we have anything in the pipeline that is used as a replacement for minoxidil?

      in Minoxidil  17 upvotes 1 year ago
      The conversation discusses hair loss treatments, focusing on alternatives to Minoxidil, such as Bimatoprost and Latanoprost, and the use of Finasteride, Dutasteride, RU58841, and microneedling. The user plans to add Latanoprost to their regimen, which already includes oral and topical Minoxidil and Finasteride, Ketoconazole shampoo, and microneedling.

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    6 / 6 results
      Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review

      research Female pattern hair loss: A clinical, pathophysiologic, and therapeutic review

      66 citations , June 2018 in “International Journal of Women's Dermatology”
      This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.
      Treatment of Hyperandrogenism in Polycystic Ovary Syndrome

      research Treatment of hyperandrogenism in polycystic ovary syndrome

      1 citations , October 2010 in “Cambridge University Press eBooks”
      This review discusses strategies for managing dermatological symptoms of hyperandrogenism in PCOS by reducing androgen levels and actions, and reports no new clinical results.
      Medical Treatment of Hirsutism

      research Medical treatment of hirsutism

      66 citations , September 2008 in “Dermatologic therapy”
      This review discusses medical treatments for hirsutism, focusing on oral contraceptives and other therapies, but reports no new results; the authors emphasize the lack of evidence for insulin sensitizers in treating hirsutism alone.
      Androgenetic Alopecia: An Evidence-Based Treatment Update

      research Androgenetic Alopecia: An Evidence-Based Treatment Update

      151 citations , May 2014 in “American Journal of Clinical Dermatology”
      This review concluded that oral finasteride for men and topical minoxidil for both genders have the most evidence supporting their effectiveness and safety for treating androgenetic alopecia.
      Medical Treatment of Hirsutism in Women

      research Medical Treatment of Hirsutism in Women

      18 citations , June 2010 in “Current medicinal chemistry”
      This review discusses current treatment options for hirsutism, emphasizing the importance of combining therapies for better outcomes, but reports no new clinical findings.