2 years on treatment (stack update)
    2/24/2025

    From the encyclopedia
    Dutasteride โ†’

    Heavy duty finasteride that comes with higher risks

    Minoxidil โ†’

    An essential vasodilator with some anti-androgenic effects

    Spironolactone โ†’

    powerful topical and oral anti-androgen used mostly by women

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    ๐Ÿ’Š Dutasteride (oral) 0.5mg daily 2 years
    ๐Ÿ’ง Minoxidil (topical) 2mL daily 2 years
    ๐Ÿ’Š Spironolactone (oral) 100mg daily 2 years
    โ€ข Estradiol Valerate (SubQ injections) 4mg weekly 2 years
    the tone is ๐Ÿ˜€ positive with significant hair improvement results.

    Other terms

    A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.
    View this post in the Community โ†’

    Similar Community Posts Join

    5 / 5 results

      community My 2 Years Progress (Hair Recovery)

       1465 upvotes 5 months ago
      A person shared their hair regrowth journey using HIMS topical treatments with finasteride, minoxidil, hormone replacement therapy (HRT), and microneedling. They also discussed their transition as a transgender woman and the positive impact of HRT on hair recovery.

      community 5 months topical spiro + minox + micro

       6 upvotes 1 year ago
      A 35-year-old male uses topical minoxidil, spironolactone, and microneedling for hair loss, with spironolactone prescribed based on a DNA test indicating poor response to finasteride and dutasteride. Despite concerns about the test's validity and spironolactone's side effects, he reports stable or improved hair condition and no low testosterone symptoms.

      community Is my current doseage viable? (Trans)

       3 upvotes 11 months ago
      The user is taking Dutasteride, Finasteride, Estradiol, Spironolactone, and Progesterone for hair regrowth and is considering adding Minoxidil and rosemary oil. They are experiencing some hair regrowth and are consulting a dermatologist to avoid a hair transplant.

    Related Research

    6 / 6 results
      Interventions for Female Pattern Hair Loss

      research Interventions for female pattern hair loss

      21 citations , May 2016 in “The Cochrane library”
      This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
      Finasteride Treatment of Hair Loss in Women

      research Finasteride Treatment of Hair Loss in Women

      29 citations , May 2010 in “Annals of Pharmacotherapy”
      This review discusses the limited objective evidence for using finasteride in women with alopecia, suggesting that it could be considered for those who don't benefit from minoxidil, but reports no new clinical results.
      Hair Loss in Women: Comprehensive Overview and Treatment Options

      research Hair Loss in Women

      81 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”
      This review discusses the classifications, diagnostic methods, and treatment strategies for female pattern hair loss, but reports no clinical results.
      Androgenetic Alopecia: An Evidence-Based Treatment Update

      research Androgenetic Alopecia: An Evidence-Based Treatment Update

      151 citations , May 2014 in “American Journal of Clinical Dermatology”
      This review concluded that oral finasteride for men and topical minoxidil for both genders have the most evidence supporting their effectiveness and safety for treating androgenetic alopecia.
      Menopause and Hair Loss in Women: Exploring the Hormonal Transition

      research Menopause and hair loss in women: Exploring the hormonal transition

      1 citations , May 2025 in “Maturitas”
      This article highlights that hormonal changes during menopause can significantly affect hair health, leading to decreased hair density, altered texture, and increased hair disorders, which may subsequently impact emotional well-being in women.
      Cross-Sex Hormone Therapy for Gender Dysphoria

      research Cross-sex hormone therapy for gender dysphoria

      21 citations , November 2014 in “Journal of Endocrinological Investigation”
      This review discusses cross-sex hormone therapy for managing gender dysphoria in transsexual individuals and reports no new clinical results; it highlights the need for education and culturally sensitive training for healthcare professionals.