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GlossaryCorticotropin-Releasing Hormone

peptide hormone that triggers stress response via ACTH release

Corticotropin-Releasing Hormone (CRH) is a peptide hormone involved in the stress response. It is produced by the hypothalamus and stimulates the pituitary gland to release adrenocorticotropic hormone (ACTH), which in turn prompts the adrenal glands to produce cortisol, a key stress hormone. CRH also plays a role in various bodily functions, including immune response and skin health, and has been linked to conditions like alopecia, where stress can exacerbate hair loss.

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research Ganoderma Lucidum Extract Attenuates Corticotropin-Releasing Hormone Induced Cellular Senescence in Human Hair Follicle Cells

April 2024 in “iScience”

Ganoderma lucidum extract may help treat stress-related hair loss.

research Stress-Related Skin Disorders

67 citations, July 2016 in “Reviews in Endocrine and Metabolic Disorders”

Stress can worsen skin conditions by affecting hormone levels and immune response.

An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

27 citations, December 2013 in “Endocrinology”

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Involvement of Neurosteroids in the Control of Hypothalamic-Pituitary-Adrenal Axis Activity in Pregnant Sheep Under Basal and Stressful Conditions

research Involvement of Neurosteroids in the Control of Hypothalamic-Pituitary-Adrenal Axis Activity in Pregnant Sheep Under Basal and Stressful Conditions

4 citations, August 2021 in “Theriogenology”

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

research Alopecia Areata Triggered by Psychological Stress and Successfully Treated with a Janus Kinase Inhibitor: Case Report

August 2022 in “Revista de la Universidad Industrial de Santander/Salud UIS”

Stress-related hair loss was reversed with a special medication.

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community How does hair loss and recovery work?

in Chat 12 upvotes 6 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.