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GlossaryEctopic ACTH Syndrome

non-pituitary tumors produce ACTH, causing excess cortisol production

Ectopic ACTH Syndrome is a condition where non-pituitary tumors, often found in the lungs, pancreas, or thymus, produce adrenocorticotropic hormone (ACTH). This leads to excessive cortisol production by the adrenal glands, causing symptoms like weight gain, high blood pressure, and muscle weakness.

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research ACTH-Dependent Cushing's Syndrome Due to Metastatic Cervical Cancer: A Case Report

October 2024 in “Journal of the Endocrine Society”

ACTH-dependent Cushing's syndrome linked to metastatic cervical cancer is rare and has high risks.

research ACTH-Dependent Cushing's Syndrome Due to Metastatic Cervical Cancer: A Case Report

October 2024 in “Journal of the Endocrine Society”

Metastatic cervical cancer can cause rare, severe Cushing's syndrome with high risk of death.

research Case 18-2018: A 45-Year-Old Woman with Hypertension, Fatigue, and Altered Mental Status

3 citations, June 2018 in “The New England Journal of Medicine”

A woman with Cushing's syndrome improved after surgery to remove a tumor causing the condition.

research Adrenal Cortex Tumors and Hyperplasias

2 citations, November 2011 in “InTech eBooks”

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

research Hyperadrenocorticism (Cushing’s Disease or Syndrome) in Dogs: Treatment Approaches and Prognosis

23 citations, February 1979 in “Veterinary Clinics of North America: Small Animal Practice”

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

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