Topical Treatment for Scarring and Non-Scarring Alopecia: An Overview of the Current Evidence

    May 2021 in “ Clinical, Cosmetic and Investigational Dermatology ”
    Camila O. Cardoso, Seila Tolentino, Taís Gratieri, Marcílio Cunha-Filho, Renata Fonseca Vianna Lopez
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    TLDR Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.
    The document "Topical Treatment for Scarring and Non-Scarring Alopecia: An Overview of the Current Evidence" reviews the effectiveness of various topical treatments for alopecia. Minoxidil and finasteride are the most effective treatments for non-scarring alopecia, with minoxidil increasing hair growth by 40% in 3-6 months. For scarring alopecia, topical corticosteroids and calcineurin inhibitors show promise, but more research is needed. The paper also discusses the use of nanoparticles in topical treatments, which can reduce irritant potential, control drug release, and increase drug penetration. Techniques like iontophoresis, sonophoresis, and microneedling are also mentioned as potential strategies for enhancing drug delivery. The document concludes by emphasizing the need for more clinical studies to determine the effectiveness and safety of these new therapeutic modalities for the treatment of hair loss.
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      community One Year Progress (Topical Fin/Min)

      in Progress Pictures  154 upvotes 1 year ago
      The user experienced significant hair regrowth over a year using topical finasteride (0.1%) and minoxidil (7%), along with Ketoconazole shampoo, and recently switched to dutasteride and plans to add oral minoxidil. They managed side effects like oily skin and itchiness with a corticosteroid and chose topical treatments initially to limit systemic exposure.

      community Been on fin/min topical spray for 6 months and my hair is the worst it’s been

      in Progress Pictures  6 upvotes 5 months ago
      The user has been using a topical spray containing finasteride and minoxidil for six months but is experiencing increased hair shedding and concerns about its effectiveness. Suggestions include switching to oral finasteride and minoxidil, consulting a dermatologist, and checking for underlying health issues like thyroid function and nutrient deficiencies.

      community Haircafe - TOPICAL minoxidil is an anti aging drug

      in Minoxidil  245 upvotes 1 year ago
      Topical minoxidil may cause skin aging effects like wrinkles and dark circles, possibly due to its alcohol content, while oral finasteride is reported to make users look younger. Switching to oral minoxidil or using moisturizers might help reduce these skin issues.

      community Betnovate Scalp for hair loss?

      in Product  2 upvotes 3 years ago
      A dermatologist prescribed Betnovate scalp, a corticosteroid, for a 21-year-old male's hair loss due to DHT. The individual is considering using Nizoral shampoo, topical finasteride, a derma roller, and minoxidil, but is unsure about the effectiveness of two other products suggested by the dermatologist.

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