Preparation and Characterization of Minoxidil Loaded Nanostructured Lipid Carriers

April 2016 in “ Aaps Pharmscitech ”

Wenxi Wang, Lina Chen, Xinyan Huang, Anna Shao

minoxidil nanostructured lipid carriers NLC topical delivery stearic acid oleic acid surfactants solid lipid nanoparticles SLNs Rogaine

From the encyclopedia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

oleic acid →

Studysummary This study found that nanostructured lipid carriers enhanced the skin penetration and retention of minoxidil compared to solid lipid nanoparticles, suggesting they could be a promising method for topical delivery.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

5 / 5 results

research Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route

95 citations , July 2015 in “European journal of pharmaceutics and biopharmaceutics”

This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.

research Investigation of Six Novel Susceptibility Loci for Male Androgenetic Alopecia in Women With Female Pattern Hair Loss

25 citations , July 2013 in “Journal of Dermatological Science”

This study suggests that the androgen receptor locus on the X chromosome may play a role in the pathogenesis of early-onset female pattern hair loss.

research Molecular Mechanisms of Androgenetic Alopecia

229 citations , August 2002 in “Experimental Gerontology”

This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.

research Androgenetic Alopecia in Men and Women

77 citations , March 2001 in “Clinics in Dermatology”

This article discusses treatment approaches for female pattern hair loss and concludes that available medical treatments are effective in reversing or stabilizing the condition in most cases of mild-to-moderate severity.

research Androgenetic Alopecia: In Vivo Models

27 citations , October 1999 in “Experimental and Molecular Pathology”

This article reviews potential animal models for studying androgenetic alopecia and reports no new experimental results; the authors highlight the need for further development of rodent models.