Molecular Mechanisms of Androgenetic Alopecia

August 2002 in “ Experimental Gerontology ”

Ralph M. Trüeb

androgenetic alopecia dihydrotestosterone androgen receptor miniaturization of hair follicles weak androgens 5alpha-reductase androgen inactivating enzymes oral finasteride topical minoxidil AGA DHT AR Propecia Rogaine

From the encyclopedia

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.

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