Drugs Affecting Hair Growth

    January 1990
    Ervin Novak
    Image of study
    TLDR Different hair growth phases affect how follicles respond to X-rays, and hormones like testosterone and dihydrotestosterone play a key role in baldness; transplanted hair can grow on bald scalp areas.
    The study from 34 years ago examined the hair growth cycles and their effects on hair follicles. It found that hair follicles respond differently to X-ray irradiation depending on their growth phase, highlighting the need for controlled studies. The research also showed that follicular growth is dependent on the interaction between the dermal papilla and the follicle's epidermal position. The study confirmed that androgen is the stimulating factor for common baldness and that hair follicles are active target organs of testosterone. The enzyme 5-alpha-reductase, more active in the growth phase, converts testosterone to dihydrotestosterone, which was found to play a significant role in androgenic alopecia. The study also demonstrated that the scalp can support hair growth when hairs are transplanted onto bald areas.
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