Testosterone Metabolism in the Skin
November 1975
in “
Archives of dermatology
”
Studysummary This review discusses testosterone metabolism in human skin and its role in androgenetic skin disorders, suggesting that temporary increases in dihydrotestosterone may lead to these conditions.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document reviewed the metabolism of testosterone in human skin and discussed the role of dihydrotestosterone (DHT) in androgenetic alopecia, acne vulgaris, and idiopathic hirsutism. It hypothesized that temporary increases in DHT formation at specific skin sites during different ages could lead to the development of normal sexual characteristics and androgen-dependent skin disorders. The potential for future treatments using antiandrogens was also considered based on recent studies.
