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Glossary Antiandrogenic

substances inhibit male sex hormones like testosterone

Antiandrogenic refers to substances or treatments that inhibit the effects of androgens, which are male sex hormones like testosterone. These substances can be used to treat conditions like androgenic alopecia (hair loss) and prostate cancer by blocking the action of these hormones, thereby reducing their influence on hair follicles and other tissues.

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Research

5 / 1000+ results

research Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships

204 citations , February 2000 in “Current Medicinal Chemistry”

This review discusses the use of antiandrogens like flutamide and its derivatives in prostate cancer treatment and highlights the need for next-generation antiandrogens for improved efficacy; it reports no new clinical results.

research Treatment of female pattern hair loss with oral antiandrogens

179 citations , March 2005 in “British Journal of Dermatology”

This study found that 88% of women with female pattern hair loss who received oral antiandrogens saw no progression or improvement in their condition.

research Antiandrogens for the Treatment of Hirsutism: A Systematic Review and Metaanalyses of Randomized Controlled Trials

150 citations , February 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

This study suggests that antiandrogens may slightly reduce hirsutism severity compared to placebo, but evidence is weak and their relative efficacy remains uncertain.

research Treatment of hirsutism with the pure antiandrogen flutamide

130 citations , September 1990 in “Journal of the American Academy of Dermatology”

This study found that combining flutamide with an oral contraceptive significantly reduced hirsutism, acne, and seborrhea in patients after seven months, without significant side effects.

research Pharmacology of antiandrogens

97 citations , November 1986 in “Journal of Steroid Biochemistry”

This review discusses the pharmacological properties and clinical applications of cyproterone acetate and similar antiandrogens, noting previous failures in local applications due to concentration limitations; it reports no new empirical results.

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Community Join

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community anti-androgens help with chronic seborric dermatitis ?! and hence diffuse thinning

7 upvotes 1 year ago

An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.

community Anti-Androgens causing hairline to recede?

in Research/Science 5 upvotes 2 years ago

Anti-androgens like Finasteride, Dutasteride, Metformin, and Topical Spironolactone cause hairline recession and increased cholesterol levels. The hairline recovers after stopping the drugs.

community Topical Anti Androgens detailed thread

6 upvotes 2 months ago

Users discuss the effectiveness of topical anti-androgens like RU58841, Pyri (KX826), and CB for hair loss. Some report maintenance and regrowth with Pyri, while others find limited success with RU58841 and switch to combinations like finasteride and minoxidil or minoxidil and dutasteride.

community Affordable anti androgens in India?

in Treatment 4 upvotes 1 year ago

The conversation discusses hair loss treatments, specifically the use of anti-androgens like RU58841 and Pyrilutamide, which are expensive in India. Alternatives like spironolactone and concerns about the effectiveness of finasteride and dutasteride are also mentioned.

community Topical anti-androgen availability in Australia

in Product 2 years ago

Availability of topical anti-androgens, especially RU58841, in Australia. Issues with customs seizures and lack of credible local sources.

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Learn

2 / 5 results

learn Pyrilutamide

Is pyrilutamide a safer alternative to oral antiandrogens like finasteride? Pyrilutamide (KX-826) is an unapproved, investigational topical antiandrogen whose safety data come from short-term sponsor announcements, not peer-reviewed studies. No study has compared it with finasteride, so there is no evidence that it is safer.

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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