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    Glossary Topical Antiandrogens

    medications applied to skin to block androgen effects locally

    Topical antiandrogens are medications applied directly to the skin to block the effects of androgens, which are hormones that can contribute to conditions like acne, hirsutism (excessive hair growth), and androgenetic alopecia (pattern hair loss). By inhibiting these hormones locally, these treatments can help manage symptoms without the systemic side effects associated with oral antiandrogens.

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    Research 10 of 1000+

    1. New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice International Journal of Pharmaceutics · 2000 · 37 citations
    2. Topical Antiandrogens Archives of Dermatology · 1985 · 11 citations
    3. Topical antiandrogens in the treatment of male-pattern baldness Clinics in dermatology · 1988 · 10 citations
    4. Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris American Journal of Clinical Dermatology · 2019 · 7 citations
    5. Topical antiandrogens. What use in dermatology? Archives of Dermatology · 1985 · 5 citations
    6. Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen Organic Process Research & Development · 2017 · 9 citations
    7. Clascoterone: a new topical antiandrogen agent. Prospects in Pharmaceutical Sciences · 2025
    8. Assessment of the efficacy of topical antiandrogen; spironolactone in patients with androgenetic alopecia by dermoscopy Journal of Pakistan Association of Dermatologists · 2022
    9. RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism The Journal of Steroid Biochemistry and Molecular Biology · 1994 · 49 citations
    10. Cortexolone 17a-propionate: Preclinical profile of a new topical, skin selective, steroidal antiandrogen Journal of the American Academy of Dermatology · 2012
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    Community 10 of 1000+

    1. Which is safest carrier for topical antiandrogens (finasteride/kx-826/ru/dutasteride) Reddit · 26 Dec 2025
    2. KX-826 and RU58841: do topical anti-androgens work? Reddit · 3 Sept 2026
    3. Topical Anti Androgens detailed thread Reddit · 28 Jul 2026
    4. Where are the so called novel topical anti androgens Reddit · 13 Jun 2026
    5. What are some topical anti androgens(not dht). Reddit · 8 Jun 2026
    6. Cheap topical anti-androgens recommendations? Reddit · 10 Dec 2025
    7. How to choose between topical antiandrogen (Pyrilutamide) vs topical Alfatradiol (17α-estradiol) as an add-on treatment? Reddit · 5 Nov 2025
    8. What's the best/"safest" topical anti androgen on the market currently? Reddit · 22 Sept 2025
    9. Topical anti-androgen availability in Australia Reddit · 2 Jul 2024
    10. Ranking of all the topical anti androgens in terms of effectivness? Reddit · 9 Oct 2022
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    Learn 3 of 26

    1. Fluridil Topical anti-androgen sold as a cosmetic lotion
    2. Pyrilutamide Experimental topical anti-androgen, also known as KX-826
    3. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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