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    Glossary Antiandrogenic

    substances inhibit male sex hormones like testosterone

    Antiandrogenic refers to substances or treatments that inhibit the effects of androgens, which are male sex hormones like testosterone. These substances can be used to treat conditions like androgenic alopecia (hair loss) and prostate cancer by blocking the action of these hormones, thereby reducing their influence on hair follicles and other tissues.

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    Research 10 of 1000+

    1. Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships Current Medicinal Chemistry · 2000 · 204 citations
    2. Pharmacology of antiandrogens Journal of Steroid Biochemistry · 1986 · 97 citations
    3. The Antiandrogenic Action of 4–Androsten–3–one–17β– Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ1 Endocrinology · 1973 · 87 citations
    4. Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women* The Journal of Clinical Endocrinology & Metabolism · 1989 · 78 citations
    5. Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction Circulation · 2015 · 56 citations
    6. The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells Nature Communications · 2021 · 50 citations
    7. Mixed “Antiandrogenic” Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat Toxicological sciences · 2018 · 49 citations
    8. Androgens and Antiandrogens Annals of the New York Academy of Sciences · 2003 · 41 citations
    9. Evaluation of the rodent Hershberger assay using three reference endocrine disrupters (androgen and antiandrogens) Reproductive Toxicology · 2003 · 37 citations
    10. Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Frontiers in Medicine · 2020 · 36 citations
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    Community 10 of 68

    1. Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens. Reddit · 7 Dec 2024
    2. Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens Community · 6 Dec 2024
    3. Is shedding a good sign for antiandrogens? Reddit · 2 Nov 2024
    4. has anyone tried rubbing receipt paper on their heads as a free topical antiandrogen? Reddit · 10 Sept 2024
    5. Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ? Reddit · 10 Sept 2024
    6. For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction? Reddit · 26 Apr 2023
    7. Anybody that regrew or thickened up hair with topical dutasteride 0.1% daily or simillar dosage? (without combining finasteride or any other antiandrogens) Reddit · 9 Nov 2021
    8. Which is safest carrier for topical antiandrogens (finasteride/kx-826/ru/dutasteride) Reddit · 26 Dec 2025
    9. How to choose between topical antiandrogen (Pyrilutamide) vs topical Alfatradiol (17α-estradiol) as an add-on treatment? Reddit · 5 Nov 2025
    10. Recommendations for topical antiandrogens Reddit · 30 Nov 2025
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    Learn 1 of 6

    1. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
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