34 citations
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April 2009 in “Skin Pharmacology and Physiology” This study found that Minoxidil had biphasic effects on normal human keratinocytes, stimulating proliferation at micromolar doses, but showing antiproliferative, pro-differentiative, and cytotoxic effects at millimolar concentrations.
72 citations
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December 1983 in “Journal of Investigative Dermatology” Minoxidil helps hair cells live longer and grow longer.
8 citations
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April 1990 in “PubMed” This study suggests that high concentrations of minoxidil may prolong the proliferative capacity of keratinocytes, which may partially explain its positive effect on hair growth.
March 1990 in “Journal of Dermatological Science” 1 citations
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January 1989 in “The Nishinihon Journal of Dermatology” In this study, minoxidil did not demonstrate any anti-aging effects on postconfluent hair follicle cells, as no difference was observed in cell proliferation or differentiation compared to controls.
19 citations
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October 1989 in “PubMed” This study found that sulfation of minoxidil occurs in hair follicles and proliferative keratinocytes, which may be linked to its hair growth stimulation effects.