In Vitro Suppression of Human Lymphocyte Activity by Minoxidil

January 1985 in “ International Journal of Dermatology ”

Gillian M.P. Galbraith, Bruce H. Thiers

minoxidil immune-suppressive human lymphocytes pattern baldness alopecia areata Rogaine

TLDR Minoxidil may help hair growth by stopping immune system attacks on hair follicles.

This 1985 study found that minoxidil has immune-suppressive effects on human lymphocytes in vitro, suggesting that it may work by suppressing the immune system's attack on hair follicles in individuals with pattern baldness or alopecia areata.

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Research cited in this study

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Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.

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Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

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. This conversation discussed the efficacy of Minoxidil and Finasteride as treatments for hair loss, with a focus on the potential side effects of taking Oral Minoxidil. Some users shared their experiences with both treatments and there was debate over whether they were safe or not.

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Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

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Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community UPDATE: The theory that explains everything. Please help me make this big!

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Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

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research In Vitro Suppression of Human Lymphocyte Activity by Minoxidil

17 citations, January 1985 in “International Journal of Dermatology”

Minoxidil may help hair growth by stopping immune system attacks on hair follicles.