Hair Characteristics and Androgenetic Alopecia in Koreans

January 2013 in “ Journal of The Korean Medical Association ”

Gwang Seong Choi

androgenetic alopecia AGA dihydrotestosterone DHT finasteride dutasteride minoxidil male pattern hair loss Propecia Avodart Rogaine

From the encyclopedia

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

Dutasteride →

Heavy duty finasteride that comes with higher risks

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary This article reviews factors influencing hair growth and treatment options for androgenetic alopecia, but it reports no new clinical results on their effectiveness.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

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research Analysis of Familial Factors Using the Basic and Specific (BASP) Classification in Korean Patients with Androgenetic Alopecia

18 citations , March 2011 in “Journal of The American Academy of Dermatology”

Familial factors affect hair loss types in Koreans, with M type in men, L type in women, and paternal factors influencing male hair loss more.

research Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla

122 citations , November 2010 in “Journal of Dermatological Science”

This study found that increased expression of type II 5α-reductase, androgen receptors, and Hic-5/ARA55 in dermal papilla cells upregulates androgen sensitivity, playing a key role in androgenetic alopecia pathogenesis.

research Nutrition and Hair Health: The Impact of Nutritional Deficiencies

70 citations , June 2010 in “Clinics in Dermatology”

This review discusses how changes in hair and skin may indicate underlying vitamin deficiencies and emphasizes the need to identify populations at risk for these deficiencies; it reports no new results.

Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

research Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

92 citations , June 2010 in “Journal of The American Academy of Dermatology”

This study found that 0.5 mg of dutasteride significantly improved hair growth compared to placebo and was well tolerated over six months in men with male pattern hair loss.

The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis

research The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis

41 citations , December 2008 in “International Journal of Dermatology”

This study observed that hair density and thickness were significantly reduced across multiple scalp sites in South Korean women with hair loss, highlighting potential patterns that could aid in differentiating hair disorders.

research Does Degree of Baldness Influence Vitamin D Status?

19 citations , December 2008 in “Medical Journal of Australia”

This study found no significant association between the degree of male-pattern baldness and serum 25-hydroxyvitamin D levels in healthy middle-aged and older men.

research Androgens and Hair Growth

209 citations , September 2008 in “Dermatologic Therapy”

This review discusses the role of androgens in hair follicle regulation and suggests that a better understanding could enhance treatments for conditions like hirsutism and alopecia, but does not present new findings.

research Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26

62 citations , March 2008 in “American Journal of Human Genetics”

This study located a potential genetic link for androgenetic alopecia on chromosome 3q26, marking an early step in identifying new susceptibility genes for male pattern baldness.

research A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification

125 citations , May 2007 in “Journal of The American Academy of Dermatology”

This study describes the development of the BASP classification system, providing a universal and systematic approach for classifying pattern hair loss in both men and women.

research Drug Reactions Affecting Hair: Diagnosis

85 citations , April 2007 in “Dermatologic Clinics”

This article reviews drug-induced hair changes, highlighting that while many drugs are occasionally linked to hair loss, this connection has been conclusively established for only a few, and such hair loss is typically reversible.

research Sexual Hormones in Human Skin

305 citations , February 2007 in “Hormone and metabolic research”

This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.

research Characteristic Features of Japanese Women's Hair With Aging and Hair Loss

76 citations , December 2006 in “Journal of Dermatological Science”

This study observed that Japanese women experience diffuse central hair loss after age 40, characterized by reduced hair density and thicker hair ratio rather than vellus-like hairs.

The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

research The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

215 citations , November 2006 in “Journal of The American Academy of Dermatology”

This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.

research Iron Deficiency and Hair Loss: The Jury Is Still Out

22 citations , April 2006 in “Journal of The American Academy of Dermatology”

This review discusses the diagnosis and treatment of iron deficiency, its potential link to hair loss, and emphasizes the importance for dermatologists to understand these aspects; it reports no new findings.

research Comparative Evaluation of Hair Density and Grouped Hair Unit Pattern Between Androgenetic Alopecia and Normal Scalp

5 citations , January 2004 in “Annals of Dermatology”

This study found that Korean men with androgenetic alopecia have lower hair density and a higher proportion of single-hair units compared to normal adult males.

research Molecular Genetic and Endocrine Mechanisms of Hair Growth

51 citations , January 2003 in “Hormone Research in Paediatrics”

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

research Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia

31 citations , January 2003 in “Dermatology”

This article provides an overview of recent discoveries about steroidogenic enzymes involved in androgenetic alopecia but reports no new clinical results.

A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , August 2002 in “Journal of The American Academy of Dermatology”

This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.

research Male Androgenetic Alopecia

54 citations , July 2002 in “Clinical and Experimental Dermatology”

This article provides a critical overview of recent discoveries in the genetics and molecular processes involved in androgenetic alopecia, focusing on its polygenic basis and DHT dependency, but reports no new clinical results.

research Female Pattern Hair Loss

226 citations , September 2001 in “Journal of The American Academy of Dermatology”

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

research Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss

116 citations , September 2001 in “Journal of The American Academy of Dermatology”

This study suggests that miniaturization in pattern hair loss may occur abruptly and can be reversed with treatment, as supported by histologic evidence in finasteride-responsive patients.

research Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss

234 citations , February 2001 in “British Journal of Dermatology”

FPHL affects hair density and diameter, causing visible hair loss in older women.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations , October 1998 in “Journal of The American Academy of Dermatology”

In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.

research Drug-Induced Hair Loss and Hair Growth

147 citations , April 1994 in “Drug Safety”

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

research The Unit Area Trichogram in the Assessment of Androgen-Dependent Alopecia

90 citations , October 1983 in “British Journal of Dermatology”

This study found that individuals with androgenic alopecia have an increased number of thin hairs (less than 40 microns in diameter) per cm², which may affect their clinical appearance.