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    Did you mean Dermal Papillae?
    Glossary Dermal Papillae

    small skin projections crucial for hair growth and nutrient supply

    Dermal papillae are small, nipple-like extensions of the dermis (the inner layer of the skin) that project into the epidermis (the outer layer of the skin). In the context of hair, they are located at the base of hair follicles and play a crucial role in hair growth by supplying nutrients and signaling molecules to the hair matrix cells, which are responsible for producing hair.

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    Community 10 of 638

    1. New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell Reddit · 24 Dec 2014
    2. HairClone (UK) finally begins offering its Dermal Papilla Cell Hair Multiplication procedure to humans. In Guatemala. Reddit · 24 Feb 2026
    3. [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression Reddit · 4 Dec 2019
    4. Hair follicle dermal papilla exosomes Reddit · 7 Jul 2025
    5. Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect Reddit · 18 Jun 2026
    6. Has anyone ever had success with just micro-needling? Reddit · 25 Apr 2024
    7. Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg Reddit · 28 Jan 2024
    8. New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been. Reddit · 2 Apr 2026
    9. Oxytocin, empathy, hair, and cinnamon Community · 12 Aug 2024
    10. How soon is hair clone? Next five years?! Reddit · 24 Jun 2024
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    Research 10 of 1000+

    1. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis Development · 2009 · 338 citations
    2. β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010 · 314 citations
    3. Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth Proceedings of the National Academy of Sciences of the United States of America · 2013 · 256 citations
    4. Differences in Hair Follicle Dermal Papilla Volume are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999 · 231 citations
    5. Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp Journal of Endocrinology · 1998 · 227 citations
    6. Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline Development · 2013 · 211 citations
    7. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003 · 208 citations
    8. Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells British Journal of Dermatology · 1998 · 192 citations
    9. Androgen‐inducible TGF‐β1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understanding paradoxical effects of androgen on human hair growth ˜The œFASEB journal · 2002 · 190 citations
    10. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014 · 184 citations
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    Learn 9 of 10

    1. SCUBE3 Signalling protein made in the hair follicle
    2. KY19382 Experimental compound that activates hair-growth signals, tested only in animals
    3. Hair Multiplication extract, clone, and reinsert your own hair cells
    4. Exosomes Tiny cell-derived particles offered by clinics as an injectable treatment
    5. Redensyl Cosmetic ingredient blend sold for thinning hair
    6. GHK-Cu Copper peptide used in skin and hair cosmetics
    7. Minoxidil Vasodilator used on the scalp and, at low doses, as a tablet
    8. Valproic acid Anti-seizure and mood-stabilising drug
    9. Stem Cell Factor
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