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    Stem Cell Factor

    also sh-Polypeptide-4, SCF, KIT-ligand, steel factor, mast cell growth factor

    Stem cell factor is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis, spermatogenesis, and melanogenesis.

    Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

    Research 10

    1. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    2. Sorafenib stimulates human skin type mast cell degranulation and maturation Journal of dermatological science · 2017 · 7 citations
    3. Stem Cell therapy for Hair Loss Medical & Clinical Research · 2025
    4. The new regenerative and innovative strategies in hair loss 2021 · 3 citations
    5. Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss Springer eBooks · 2016
    6. Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles Journal of Endocrinology · 2008 · 39 citations
    7. THE EFFECT OF HAIR TONIC FROM SECRETOME MESENCHYMAL STEM CELL ON HAIR GROWTH IN HAIR LOSS CASES International Journal of Applied Pharmaceutics · 2026
    8. Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts Laboratory Investigation · 2006 · 27 citations
    9. The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse Stem cell research & therapy · 2022 · 2 citations
    10. Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis Cell Stem Cell · 2021 · 23 citations
    All research on Stem Cell Factor →

    Community 10

    1. Scalp Microneedling with Stemcell and Exohealer Reddit · 12 Jun 2026
    2. Calecim (PTT-6) Advanced Hair System with Topical Exosomes and Growth Factors for Hair Growth Reddit · 22 Sept 2024
    3. NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress Reddit · 9 Jun 2024
    4. 12 mo 1 ml daily Min/Dermaroller 1mm-1.5mm update + AGA progression theory and specific order of treatment Reddit · 22 Jan 2021
    5. Starting the microneedling only journey. M35 with diffuse thinning. Derminator 2, keto, vitamins and castor oil. Reddit · 31 Mar 2022
    6. Anyone Try Microneedling with Exosomes/AAPE? Reddit · 6 May 2022
    7. How Does Exosome Therapy Work for Hair Loss? Reddit · 13 Oct 2023
    8. Physio-metabolic method (antiandrogen, minoxidil, leg training and cold) Community · 7 Jun 2024
    9. Stem cells for hair, does it work? Reddit · 30 Nov 2025
    10. Recent trials investigating mesenchymal stem cell derived exosomes demonstrate significant increases in anagen duration and hair shaft caliber by upregulating Wnt/beta-catenin pathways. Reddit · 24 Aug 2026
    All community posts on Stem Cell Factor →