The Role of ATP-Dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity
January 2018
in “
Stem cell biology and regenerative medicine
”
ATP-dependent chromatin remodeling epidermal differentiation skin stem cell activity hair follicle development wound healing SWI2/SNF2 family BRG1 BRM ATPases keratinocyte differentiation ACTL6a KLF4 Mi-2ß/CHD4 barrier formation p63 MAF:MAFB lncRNAs TINCR lncRNAs ANCR epidermal differentiation complex EDC locus hair regeneration chromatin remodeling skin pathophysiology tumor suppressors ATP-DCR BRM Mi-2ß CHD4 MAF MAFB TINCR ANCR EDC
Studysummary This paper reviews the role of ATP-dependent chromatin remodeling complexes in epidermal homeostasis, hair regeneration, and skin repair, noting contributions to 3D-genomic organization and suppression of UV-induced hyper-proliferation, without presenting new results.
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