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Research

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research Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology

February 2026 in “American Journal of Clinical Dermatology”

This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.

Skin Aging in Women: Pathophysiology and Treatment

research Skin Ageing in Women: Pathophysiology and Treatment

September 1999 in “The Journal of The British Menopause Society”

This review discusses how menopause and hormone replacement therapy affect skin aging in women but reports no new clinical findings.

research Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders

January 2025 in “International Journal of Molecular Sciences”

This narrative review explored the complex interconnections between psoriasis and other dermatological conditions like vitiligo, alopecia areata, and atopic dermatitis, highlighting shared immune dysfunctions that complicate diagnosis and treatment, with implications for research and holistic patient care.

research TRP Channels in Skin Biology and Pathophysiology

124 citations , December 2016 in “Pharmaceuticals”

This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.

research Pathophysiology of Insulin Resistance and Related Skin Diseases ( Review Article)

2 citations , December 2024 in “Sohag Medical Journal”

This paper discusses insulin resistance's effects on skin physiology, emphasizes its role in keratinocyte balance, and reports no new experimental findings.

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Community Join

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community Finasteride success for androgenic alopecia by a 27M physician (NO PICTURES)

4 upvotes 10 years ago

A 27-year-old male physician improved hair density using minoxidil 5% foam and finasteride 1mg every other day, with initial sexual side effects that subsided. He recommends trying finasteride for a year but warns against dutasteride due to potential liver effects.

community dut doomers - any photo evidence of people regrowing AFTER going back to fin?

in Finasteride/Dutasteride 23 upvotes 10 months ago

Some users experience worsening hair loss with dutasteride and improvement after switching back to finasteride, while others find better results with dutasteride. The effectiveness of treatments like finasteride, dutasteride, minoxidil, and RU58841 varies, requiring individuals to try different combinations or dosages to find what works best.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community 1ish year on fin and no improvement

85 upvotes 1 year ago

The user has been using finasteride for over a year without improvement and recently started oral minoxidil. Suggestions include trying dutasteride and continuing minoxidil for potential regrowth.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

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Learn

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learn Stem Cell Factor

learn Overview

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Clinics

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Experts

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36
SMP Specialist
Noelle Skin
Nice, France

Noelle Skin