Sensitive Skin

The 2013 document describes sensitive skin as a condition marked by abnormal sensations such as stinging, burning, pain, pruritus, and tingling, triggered by physical, chemical, psychological, or hormonal factors. It affects roughly 50% of the population, more commonly women, and tends to increase with age. The pathophysiology is not fully understood but may involve neurogenic inflammation and activation of sensory proteins, particularly TRP channels. Diagnosis is mainly through patient history, as there are often no histological abnormalities. Treatment involves using cosmetics cautiously or selecting products without preservatives and surfactants, or those containing neurogenic inflammation inhibitors. The document also notes the lack of consensus on diagnostic methods, the heterogeneous nature of the condition, and the need for standardized definitions and diagnostic criteria. It mentions that the author has consulted for cosmetic companies but has no other financial interests.