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GlossaryTransient Receptor Potential Channels (TRP channels)

ion channels involved in sensory perception and physiological processes

Transient Receptor Potential (TRP) channels are a group of ion channels located in the cell membrane that play a crucial role in various physiological processes, including sensation and temperature regulation. These channels respond to a wide range of stimuli, such as temperature changes, pH levels, and mechanical stress, and are involved in sensory functions like pain perception and taste.

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TRP Channels in Skin Biology and Pathophysiology

research TRP Channels in Skin Biology and Pathophysiology

124 citations , December 2016 in “Pharmaceuticals”

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

research Effects of Transient Receptor Potential (TRP) Channel Agonists and Antagonists on Slowly Adapting Type II Mechanoreceptors in the Rat Sinus Hair Follicle

13 citations , December 2009 in “Journal of the Peripheral Nervous System”

TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.

research Multimodal Roles of Transient Receptor Potential Channel Activation in Inducing Pathological Tissue Scarification

7 citations , August 2023 in “Frontiers in Immunology”

Targeting TRP channels may help reduce excessive scarring.

research Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6

January 2019 in “Columbia Academic Commons (Columbia University)”

TRPV3 and TRPV6 channels change structure to regulate calcium and heat responses.

research The Itchy Scalp: Scratching for an Explanation

61 citations , October 2011 in “Experimental dermatology”

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

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