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GlossaryTumor Protein p63 (p63)

protein crucial for epithelial tissue development and maintenance

Tumor Protein p63 (often referred to as p63 or TP63) is a protein that plays a crucial role in the development and maintenance of epithelial tissues, which are the layers of cells covering surfaces and lining cavities in the body. It is involved in regulating cell proliferation, differentiation, and apoptosis (programmed cell death). Mutations in the TP63 gene can lead to various developmental disorders and have been linked to certain types of cancer.

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research The Role of ATP-Dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity

January 2018 in “Stem cell biology and regenerative medicine”

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

research The Paradox of p53: What, How, and Why?

64 citations , July 2016 in “Cold Spring Harbor Perspectives in Medicine”

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

research Induced Pluripotent Stem Cell Derived Keratinocyte Differentiation from Reprogrammed Blood Cells

April 2017 in “Journal of Investigative Dermatology”

Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.

research MicroRNA/mRNA Regulatory Networks in the Control of Skin Development and Regeneration

56 citations , February 2012 in “Cell Cycle”

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

research Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

13 citations , January 2012 in “Dermatology”

Eruptive vellus hair cysts are rare, benign skin lesions that are hard to treat.

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community Should I continue trusting the process or be worried?

P6391 in General 62 upvotes 8 months ago

The user has been using topical minoxidil, topical finasteride, microneedling, and ketoconazole shampoo for 9 months with positive results but is concerned about recent increased shedding. Another user advises that shedding is normal and suggests continuing the treatments consistently for up to a year to see solid results.