Stem Cell and Extracellular Matrix-Related Molecules Increase Following Melatonin Treatment in the Skin of Postmenopausal Rats

April 2014 in “ Cell biology international ”

Serap Uslu, Gülperi Öktem, Ayşegül Uysal, Burak Cem Soner, Serap Arbak, Ümit İnce

melatonin epidermal thickness subcutaneous fat layer elastic fibers fibroblast growth factor β collagen type I fibronectin β-catenin c-Myc FGF β type I collagen

Studysummary This study found that melatonin treatment increased epidermal thickness, subcutaneous fat, and dermal-related factors in postmenopausal rats, suggesting benefits for skin structure after menopause.

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research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions

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research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis

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research Epidermal Stem Cells: Practical Perspectives and Potential Uses

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research Human Skin Stem Cells and the Aging Process

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This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

research Melatonin as a Major Skin Protectant: From Free Radical Scavenging to DNA Damage Repair

160 citations , July 2008 in “Experimental dermatology”

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research More Than One Way to Skin

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research Epidermal Notch Signaling: Differentiation, Cancer, and Adhesion

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research Stem Cell Factor/c-Kit Signaling in Normal and Androgenetic Alopecia Hair Follicles

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research Melatonin in the Skin: Synthesis, Metabolism, and Functions

252 citations , January 2008 in “Trends in Endocrinology and Metabolism”

This review discusses the protective and stress-buffering roles of melatonin in skin functions and structures but does not present new clinical findings.

research Expression of the Beta-Catenin Gene in the Skin of Embryonic Geese During Feather Bud Development

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research Biology of Estrogens in Skin: Implications for Skin Aging

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research Changes in Different Melanocyte Populations During Hair Follicle Involution (Catagen)

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