Protective Effects of Melatonin on the Skin: Future Perspectives

The document from October 7, 2019, discussed the protective effects of melatonin on the skin. Melatonin, primarily known for regulating sleep, was found to have antioxidant properties that can protect the skin from free radical damage. It was suggested that melatonin could be used in the treatment of skin diseases, including alopecia, due to its ability to stimulate hair growth. The document reviewed studies on melatonin's protective functions in dermal cells, its benefits for skin aging, wound healing, and various skin pathologies. It was found to prevent UV-induced damage, reduce reactive oxygen species production, and have radioprotective effects. Topical application of melatonin was suggested as a more efficient method than oral administration, with studies showing it could penetrate the skin and provide prolonged release. It was found to protect against UV radiation damage, improve skin hydration, reduce skin roughness, and improve the appearance of wrinkles. It was also effective in treating alopecia, increasing hair density and thickness while reducing hair loss. However, the document emphasized the need for further research to fully understand melatonin's effects on the skin and establish its efficacy and safety.